Protein: PYR1
Multifunctional protein CAD (Carbamoyl phosphate synthetase 2-aspartate transcarbamylase-dihydroorotase) [Includes: Glutamine-dependent carbamoyl phosphate synthase (EC 6.3.5.5); Glutamine amidotransferase (GATase) (GLNase) (EC 3.5.1.2); Ammonium-dependent carbamoyl phosphate synthase (CPS) (CPSase) (EC 6.3.4.16); Aspartate carbamoyltransferase (EC 2.1.3.2); Dihydroorotase (EC 3.5.2.3)]

Gene: PYR1, CAD
Organism: Homo sapiens
Interactions: 359
UniProt ID: P27708

Gene Ontology (top 5):
GO:0001889 - liver development
GO:0004070 - aspartate carbamoyltransferase activity
GO:0004087 - carbamoyl-phosphate synthase (ammonia) activity
GO:0004088 - carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GO:0004151 - dihydroorotase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

697438

PYR1
Multifunctional protein CAD

2

18

Small-scale

0.777

High

697520

ILK
Scaffold protein ILK

4

3

High-throughput

0.704

High

697627

M3K14
Mitogen-activated protein kinase kinase kinase 14

4

6

High-throughput

0.683

High

395535

ESR1
Estrogen receptor

4

1

High-throughput

0.666

High

697492

GRB2
Growth factor receptor-bound protein 2

3

6

High-throughput

0.650

High

697508

LG3BP
Galectin-3-binding protein

3

3

High-throughput

0.643

High

240816

PRKN
E3 ubiquitin-protein ligase parkin

3

9

High-throughput

0.640

High

413240

P53
Cellular tumor antigen p53

3

1

High-throughput

0.640

High

697461

YAP1
Transcriptional coactivator YAP1

3

13

High-throughput

0.640

High

697571

TBA1A
Tubulin alpha-1A chain

3

12

High-throughput

0.624

High

697491

1433E
14-3-3 protein epsilon

2

3

Small-scale

0.611

High

697493

1433Z
14-3-3 protein zeta/delta

2

8

High-throughput

0.611

High

697567

RICTR
Rapamycin-insensitive companion of mTOR

2

2

Small-scale

0.611

High

697628

DNJC7
DnaJ homolog subfamily C member 7

2

4

High-throughput

0.611

High

697450

CCNF
Cyclin-F

2

2

High-throughput

0.601

High

411402

NTRK1
High affinity nerve growth factor receptor

2

9

High-throughput

0.594

High

259481

BRD4
Bromodomain-containing protein 4

2

3

High-throughput

0.584

High

271916

OBSL1
Obscurin-like protein 1

2

1

High-throughput

0.584

High

345401

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

2

1

High-throughput

0.584

High

697505

TF65
Transcription factor p65

2

4

High-throughput

0.584

High

697528

CUL3
Cullin-3

2

4

High-throughput

0.584

High

697558

RC3H1
Roquin-1

2

1

High-throughput

0.584

High

697605

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

2

3

Small-scale

0.584

High

697651

SPRTN
DNA-dependent metalloprotease SPRTN

2

1

Small-scale

0.584

High

697668

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

2

1

High-throughput

0.584

High

697682

HDAC6
Protein deacetylase HDAC6

2

6

Small-scale

0.584

High

563241

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.576

High

193211

SOCS1
Suppressor of cytokine signaling 1

2

4

High-throughput

0.571

High

440387

FYN
Tyrosine-protein kinase Fyn

2

3

High-throughput

0.571

High

486662

FGR
Tyrosine-protein kinase Fgr

2

3

High-throughput

0.571

High

557112

SRC
Proto-oncogene tyrosine-protein kinase Src

2

3

High-throughput

0.571

High

584477

VAV
Proto-oncogene vav

2

7

High-throughput

0.571

High

622410

ELK1
ETS domain-containing protein Elk-1

2

1

High-throughput

0.571

High

697451

CSK
Tyrosine-protein kinase CSK

2

4

High-throughput

0.571

High

697457

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

8

High-throughput

0.571

High

697488

RHOA
Transforming protein RhoA

2

2

High-throughput

0.571

High

697502

KPCE
Protein kinase C epsilon type

2

1

High-throughput

0.571

High

697503

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

2

8

High-throughput

0.571

High

697506

KPCZ
Protein kinase C zeta type

2

2

High-throughput

0.571

High

697511

DUS4
Dual specificity protein phosphatase 4

2

2

High-throughput

0.571

High

697512

PAK1
Serine/threonine-protein kinase PAK 1

2

4

High-throughput

0.571

High

697514

MK07
Mitogen-activated protein kinase 7

2

9

High-throughput

0.571

High

697519

GRB10
Growth factor receptor-bound protein 10

2

7

High-throughput

0.571

High

697527

HDAC1
Histone deacetylase 1

2

7

High-throughput

0.571

High

697559

MEX3C
RNA-binding E3 ubiquitin-protein ligase MEX3C

2

1

Small-scale

0.571

High

697479

PPP5
Serine/threonine-protein phosphatase 5

1

7

High-throughput

0.554

High

277894

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

631071

RAB5A
Ras-related protein Rab-5A

2

0

High-throughput

0.547

High

697586

ABI1
Abl interactor 1

2

0

High-throughput

0.547

High

697609

BAD
Bcl2-associated agonist of cell death

2

0

High-throughput

0.547

High

697620

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

697629

RAD9A
Cell cycle checkpoint control protein RAD9A

1

0

Small-scale

0.537

High

161950

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

8

High-throughput

0.536

High

165698

PPE1
Serine/threonine-protein phosphatase with EF-hands 1

1

6

High-throughput

0.536

High

174939

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.536

High

256525

TBX19
T-box transcription factor TBX19

1

1

High-throughput

0.536

High

457244

TBB5
Tubulin beta chain

1

6

High-throughput

0.536

High

534674

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.536

High

697440

SHC1
SHC-transforming protein 1

1

2

High-throughput

0.536

High

697454

HD
Huntingtin

1

5

High-throughput

0.536

High

697456

GRK6
G protein-coupled receptor kinase 6

1

5

High-throughput

0.536

High

697476

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

5

High-throughput

0.536

High

697477

NEK4
Serine/threonine-protein kinase Nek4

1

5

High-throughput

0.536

High

697480

LIMK1
LIM domain kinase 1

1

7

High-throughput

0.536

High

697481

LIMK2
LIM domain kinase 2

1

2

High-throughput

0.536

High

697494

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

1

High-throughput

0.536

High

697518

G3BP1
Ras GTPase-activating protein-binding protein 1

1

4

High-throughput

0.536

High

697530

TRI29
Tripartite motif-containing protein 29

1

3

High-throughput

0.536

High

697551

MK06
Mitogen-activated protein kinase 6

1

10

High-throughput

0.536

High

697565

PKN3
Serine/threonine-protein kinase N3

1

2

High-throughput

0.536

High

697577

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

1

High-throughput

0.536

High

697579

ST32C
Serine/threonine-protein kinase 32C

1

4

High-throughput

0.536

High

697585

CDK20
Cyclin-dependent kinase 20

1

4

High-throughput

0.536

High

697595

ARRD4
Arrestin domain-containing protein 4

1

2

High-throughput

0.536

High

697599

RIN3
Ras and Rab interactor 3

1

1

High-throughput

0.536

High

697608

M4K1
Mitogen-activated protein kinase kinase kinase kinase 1

1

5

High-throughput

0.536

High

697616

HDA11
Histone deacetylase 11

1

8

High-throughput

0.536

High

697621

LOXL4
Lysyl oxidase homolog 4

1

2

High-throughput

0.536

High

697625

TESK2
Dual specificity testis-specific protein kinase 2

1

2

High-throughput

0.536

High

697634

TBA1C
Tubulin alpha-1C chain

1

12

High-throughput

0.536

High

697637

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

5

High-throughput

0.536

High

697640

DUS16
Dual specificity protein phosphatase 16

1

3

High-throughput

0.536

High

697644

STK33
Serine/threonine-protein kinase 33

1

1

High-throughput

0.536

High

697654

P63
Tumor protein 63

1

1

Small-scale

0.536

High

697655

TXNIP
Thioredoxin-interacting protein

1

2

High-throughput

0.536

High

697661

WDR76
WD repeat-containing protein 76

1

8

High-throughput

0.536

High

697669

PAK6
Serine/threonine-protein kinase PAK 6

1

5

High-throughput

0.536

High

697673

LATS2
Serine/threonine-protein kinase LATS2

1

7

High-throughput

0.536

High

697674

NRBP2
Nuclear receptor-binding protein 2

1

6

High-throughput

0.536

High

697686

MRT4
mRNA turnover protein 4 homolog

1

2

High-throughput

0.536

High

697688

G3BP2
Ras GTPase-activating protein-binding protein 2

1

4

High-throughput

0.536

High

697549

CDC37
Hsp90 co-chaperone Cdc37

1

1

High-throughput

0.515

High

62287

MTMRB
Myotubularin-related protein 11

1

0

High-throughput

0.513

High

570838

MIF
Macrophage migration inhibitory factor

1

0

High-throughput

0.513

High

697462

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

697474

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

697516

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

697541

TEBP
Prostaglandin E synthase 3

1

0

High-throughput

0.513

High

697550

PDK4
[Pyruvate dehydrogenase

1

0

High-throughput

0.513

High

697556

VWA2
von Willebrand factor A domain-containing protein 2

1

0

High-throughput

0.513

High

697581

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

High-throughput

0.513

High

697598

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.513

High

697610

IRF7
Interferon regulatory factor 7

1

0

High-throughput

0.513

High

697647

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

697656

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

0

High-throughput

0.513

High

697460

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

9

High-throughput

0.501

High

697485

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

High-throughput

0.501

High

697495

XIAP
E3 ubiquitin-protein ligase XIAP

1

2

High-throughput

0.501

High

181488

TBXT
T-box transcription factor T

1

1

High-throughput

0.500

High

464825

SP1
Transcription factor Sp1

1

3

High-throughput

0.500

High

697603

SP7
Transcription factor Sp7

1

3

High-throughput

0.500

High

697546

SMAD2
Mothers against decapentaplegic homolog 2

1

0

Small-scale

0.493

High

697453

I12R1
Interleukin-12 receptor subunit beta-1

1

1

High-throughput

0.489

High

697489

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

125252

LEG9
Galectin-9

1

2

High-throughput

0.479

High

127764

IKBE
NF-kappa-B inhibitor epsilon

1

3

High-throughput

0.479

High

131748

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

8

High-throughput

0.479

High

143565

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

1

6

High-throughput

0.479

High

156980

CTRO
Citron Rho-interacting kinase

1

5

High-throughput

0.479

High

213821

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

2

High-throughput

0.479

High

238401

RAD21
Double-strand-break repair protein rad21 homolog

1

1

High-throughput

0.479

High

257349

PAGE4
P antigen family member 4

1

2

High-throughput

0.479

High

284071

SRS10
Serine/arginine-rich splicing factor 10

1

1

Small-scale

0.479

High

315152

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

318629

RHBT1
Rho-related BTB domain-containing protein 1

1

6

High-throughput

0.479

High

325691

UBR5
E3 ubiquitin-protein ligase UBR5

1

10

Small-scale

0.479

High

340830

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

1

5

High-throughput

0.479

High

342755

HERC2
E3 ubiquitin-protein ligase HERC2

1

10

High-throughput

0.479

High

348983

LATS1
Serine/threonine-protein kinase LATS1

1

7

High-throughput

0.479

High

349814

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

371227

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

405817

MYCN
N-myc proto-oncogene protein

1

3

High-throughput

0.479

High

417957

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

420376

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

1

High-throughput

0.479

High

425328

ISG15
Ubiquitin-like protein ISG15

1

12

High-throughput

0.479

High

436801

K1C18
Keratin, type I cytoskeletal 18

1

3

High-throughput

0.479

High

465415

IGF1R
Insulin-like growth factor 1 receptor

1

8

High-throughput

0.479

High

521210

ARAF
Serine/threonine-protein kinase A-Raf

1

5

High-throughput

0.479

High

536552

HSP7C
Heat shock cognate 71 kDa protein

1

3

High-throughput

0.479

High

540815

ERG
Transcriptional regulator ERG

1

2

Small-scale

0.479

High

565167

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

577628

PLAK
Junction plakoglobin

1

1

High-throughput

0.479

High

587972

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

605563

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

6

Small-scale

0.479

High

606268

CEBPB
CCAAT/enhancer-binding protein beta

1

2

High-throughput

0.479

High

621562

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

2

High-throughput

0.479

High

622524

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

2

High-throughput

0.479

High

623119

RO52
E3 ubiquitin-protein ligase TRIM21

1

1

High-throughput

0.479

High

629581

BTF3
Transcription factor BTF3

1

1

High-throughput

0.479

High

630208

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

2

High-throughput

0.479

High

651162

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.479

High

655709

TBG1
Tubulin gamma-1 chain

1

11

High-throughput

0.479

High

667545

CDK2
Cyclin-dependent kinase 2

1

4

High-throughput

0.479

High

693239

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

1

High-throughput

0.479

High

694682

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

697441

STIP1
Stress-induced-phosphoprotein 1

1

3

High-throughput

0.479

High

697442

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

697444

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

697446

BMR1A
Bone morphogenetic protein receptor type-1A

1

1

High-throughput

0.479

High

697448

BRCA1
Breast cancer type 1 susceptibility protein

1

4

High-throughput

0.479

High

697455

MATR3
Matrin-3

1

1

High-throughput

0.479

High

697459

MAP1B
Microtubule-associated protein 1B

1

3

High-throughput

0.479

High

697463

GRIA4
Glutamate receptor 4

1

3

Small-scale

0.479

High

697465

KC1A
Casein kinase I isoform alpha

1

2

High-throughput

0.479

High

697468

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

5

High-throughput

0.479

High

697470

MCM2
DNA replication licensing factor MCM2

1

5

High-throughput

0.479

High

697471

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.479

High

697472

CDK9
Cyclin-dependent kinase 9

1

7

High-throughput

0.479

High

697473

MECP2
Methyl-CpG-binding protein 2

1

3

High-throughput

0.479

High

697475

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.479

High

697483

TERA
Transitional endoplasmic reticulum ATPase

1

9

High-throughput

0.479

High

697487

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.479

High

697490

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

697497

HSF1
Heat shock factor protein 1

1

2

High-throughput

0.479

High

697498

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

3

High-throughput

0.479

High

697499

RELB
Transcription factor RelB

1

4

High-throughput

0.479

High

697500

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

697501

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

697510

TRAF2
TNF receptor-associated factor 2

1

2

High-throughput

0.479

High

697515

M3K1
Mitogen-activated protein kinase kinase kinase 1

1

4

High-throughput

0.479

High

697517

TIF1B
Transcription intermediary factor 1-beta

1

7

High-throughput

0.479

High

697521

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

697522

NFAC2
Nuclear factor of activated T-cells, cytoplasmic 2

1

5

High-throughput

0.479

High

697523

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

697524

SQSTM
Sequestosome-1

1

3

High-throughput

0.479

High

697526

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

6

High-throughput

0.479

High

697529

DX39B
Spliceosome RNA helicase DDX39B

1

3

High-throughput

0.479

High

697532

RBM39
RNA-binding protein 39

1

1

High-throughput

0.479

High

697535

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

3

Small-scale

0.479

High

697536

CUL7
Cullin-7

1

2

High-throughput

0.479

High

697539

TNIP1
TNFAIP3-interacting protein 1

1

6

High-throughput

0.479

High

697540

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

2

High-throughput

0.479

High

697542

NCOA2
Nuclear receptor coactivator 2

1

1

Small-scale

0.479

High

697545

RHOH
Rho-related GTP-binding protein RhoH

1

3

High-throughput

0.479

High

697547

EZH2
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.479

High

697548

CCDC6
Coiled-coil domain-containing protein 6

1

2

High-throughput

0.479

High

697552

SMU1
WD40 repeat-containing protein SMU1

1

4

High-throughput

0.479

High

697554

LARP7
La-related protein 7

1

1

High-throughput

0.479

High

697562

VIR
Protein virilizer homolog

1

2

High-throughput

0.479

High

697563

ZN746
Zinc finger protein 746

1

1

High-throughput

0.479

High

697569

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

697570

MOB3C
MOB kinase activator 3C

1

1

High-throughput

0.479

High

697572

ASXL2
Putative Polycomb group protein ASXL2

1

1

High-throughput

0.479

High

697575

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

697576

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

9

High-throughput

0.479

High

697578

ZN598
E3 ubiquitin-protein ligase ZNF598

1

1

High-throughput

0.479

High

697582

ASXL1
Polycomb group protein ASXL1

1

1

High-throughput

0.479

High

697584

SLX4
Structure-specific endonuclease subunit SLX4

1

2

High-throughput

0.479

High

697587

RPTOR
Regulatory-associated protein of mTOR

1

3

High-throughput

0.479

High

697588

CNTRB
Centrobin

1

1

High-throughput

0.479

High

697589

AHI1
Jouberin

1

5

High-throughput

0.479

High

697590

RHG24
Rho GTPase-activating protein 24

1

3

High-throughput

0.479

High

697591

FBXW8
F-box/WD repeat-containing protein 8

1

4

High-throughput

0.479

High

697592

SIR6
NAD-dependent protein deacylase sirtuin-6

1

6

High-throughput

0.479

High

697593

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.479

High

697597

COP1
E3 ubiquitin-protein ligase COP1

1

6

High-throughput

0.479

High

697601

POC1B
POC1 centriolar protein homolog B

1

3

High-throughput

0.479

High

697604

TOPB1
DNA topoisomerase 2-binding protein 1

1

1

High-throughput

0.479

High

697607

HDAC2
Histone deacetylase 2

1

7

High-throughput

0.479

High

697611

FBXW7
F-box/WD repeat-containing protein 7

1

3

High-throughput

0.479

High

697613

ARMC5
Armadillo repeat-containing protein 5

1

2

High-throughput

0.479

High

697614

CHM4C
Charged multivesicular body protein 4c

1

2

High-throughput

0.479

High

697615

OPTN
Optineurin

1

4

High-throughput

0.479

High

697618

SPDLY
Protein Spindly

1

4

High-throughput

0.479

High

697619

RNF31
E3 ubiquitin-protein ligase RNF31

1

3

High-throughput

0.479

High

697623

KCTD7
BTB/POZ domain-containing protein KCTD7

1

8

Small-scale

0.479

High

697624

CIC
Protein capicua homolog

1

2

High-throughput

0.479

High

697626

RUFY1
RUN and FYVE domain-containing protein 1

1

3

High-throughput

0.479

High

697630

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

2

High-throughput

0.479

High

697632

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.479

High

697633

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

2

High-throughput

0.479

High

697635

RIOK1
Serine/threonine-protein kinase RIO1

1

3

High-throughput

0.479

High

697639

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

3

High-throughput

0.479

High

697642

YTHD1
YTH domain-containing family protein 1

1

1

High-throughput

0.479

High

697645

TRI55
Tripartite motif-containing protein 55

1

16

High-throughput

0.479

High

697646

RHBT2
Rho-related BTB domain-containing protein 2

1

6

High-throughput

0.479

High

697648

TRI31
E3 ubiquitin-protein ligase TRIM31

1

8

High-throughput

0.479

High

697649

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.479

High

697658

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

2

High-throughput

0.479

High

697659

PKHA4
Pleckstrin homology domain-containing family A member 4

1

9

High-throughput

0.479

High

697662

UNKL
Putative E3 ubiquitin-protein ligase UNKL

1

2

High-throughput

0.479

High

697663

RC3H2
Roquin-2

1

3

High-throughput

0.479

High

697664

RHOF
Rho-related GTP-binding protein RhoF

1

4

High-throughput

0.479

High

697667

BRD7
Bromodomain-containing protein 7

1

1

High-throughput

0.479

High

697670

ANLN
Anillin

1

1

High-throughput

0.479

High

697671

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

6

High-throughput

0.479

High

697672

FBX6
F-box only protein 6

1

1

High-throughput

0.479

High

697675

PIHD1
PIH1 domain-containing protein 1

1

5

High-throughput

0.479

High

697678

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

1

High-throughput

0.479

High

697680

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

5

High-throughput

0.479

High

697681

SYLC
Leucine--tRNA ligase, cytoplasmic

1

3

High-throughput

0.479

High

697683

KS6B2
Ribosomal protein S6 kinase beta-2

1

5

High-throughput

0.479

High

697684

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

697685

TES
Testin

1

1

High-throughput

0.479

High

697687

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

697689

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.479

High

697690

TRI33
E3 ubiquitin-protein ligase TRIM33

1

7

High-throughput

0.479

High

697691

SMC3
Structural maintenance of chromosomes protein 3

1

1

High-throughput

0.479

High

697692

HDAC5
Histone deacetylase 5

1

7

High-throughput

0.479

High

697696

LOXL2
Lysyl oxidase homolog 2

1

2

High-throughput

0.479

High

697697

RIPK3
Receptor-interacting serine/threonine-protein kinase 3

1

3

High-throughput

0.479

High

697698

YTHD2
YTH domain-containing family protein 2

1

1

High-throughput

0.479

High

697699

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.479

High

194004

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

221721

TPPC3
Trafficking protein particle complex subunit 3

1

0

High-throughput

0.458

High

247687

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

293243

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

299071

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

319427

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

324563

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

352329

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

376721

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.458

High

437099

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

555340

SKI
Ski oncogene

1

0

Small-scale

0.458

High

642639

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

664641

CCND1
G1/S-specific cyclin-D1

1

0

High-throughput

0.458

High

697439

DPOD1
DNA polymerase delta catalytic subunit

1

0

High-throughput

0.458

High

697443

NOS2
Nitric oxide synthase, inducible

1

0

High-throughput

0.458

High

697447

ZEB1
Zinc finger E-box-binding homeobox 1

1

0

Small-scale

0.458

High

697449

VHL
von Hippel-Lindau disease tumor suppressor

1

0

Small-scale

0.458

High

697452

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

697466

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

697467

FAS
Fatty acid synthase

1

0

Small-scale

0.458

High

697482

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

697507

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.458

High

697513

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

0

Small-scale

0.458

High

697533

NBR1
Next to BRCA1 gene 1 protein

1

0

High-throughput

0.458

High

697537

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

697538

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.458

High

697543

TRADD
Tumor necrosis factor receptor type 1-associated DEATH domain protein

1

0

High-throughput

0.458

High

697544

TRIP4
Activating signal cointegrator 1

1

0

High-throughput

0.458

High

697561

OTU1
Ubiquitin thioesterase OTU1

1

0

High-throughput

0.458

High

697574

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.458

High

697580

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

697596

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.458

High

697600

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

697602

FBX25
F-box only protein 25

1

0

High-throughput

0.458

High

697612

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

Small-scale

0.458

High

697622

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

697631

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.458

High

697636

DERL1
Derlin-1

1

0

Small-scale

0.458

High

697641

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

697643

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

0

High-throughput

0.458

High

697653

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

697660

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

697666

SHCAF
SIN3-HDAC complex-associated factor

1

0

Small-scale

0.458

High

697676

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

0

High-throughput

0.458

High

697677

MKS1
Tectonic-like complex member MKS1

1

0

High-throughput

0.458

High

697679

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

697695

FBX7
F-box only protein 7

1

0

High-throughput

0.458

High

104108

F5H1C8
Solute carrier family 15 member 3

1

1

High-throughput

0.445

High

327814

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

6

High-throughput

0.445

High

421540

A4
Amyloid-beta precursor protein

1

1

Small-scale

0.445

High

429346

JUN
Transcription factor Jun

1

2

High-throughput

0.445

High

619521

VCAM1
Vascular cell adhesion protein 1

1

3

High-throughput

0.445

High

697458

RS9
Small ribosomal subunit protein uS4

1

1

Small-scale

0.445

High

697464

SOX2
Transcription factor SOX-2

1

1

High-throughput

0.445

High

697478

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.445

High

697484

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

697486

GBRL2
Gamma-aminobutyric acid receptor-associated protein-like 2

1

6

High-throughput

0.445

High

697509

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

1

High-throughput

0.445

High

697525

TBB3
Tubulin beta-3 chain

1

6

High-throughput

0.445

High

697534

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

2

High-throughput

0.445

High

697557

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

697606

ESR2
Estrogen receptor beta

1

1

High-throughput

0.445

High

697650

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

6

High-throughput

0.445

High

697652

GBRL1
Gamma-aminobutyric acid receptor-associated protein-like 1

1

6

High-throughput

0.445

High

697657

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

6

High-throughput

0.445

High

697693

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

124240

HAX1
HCLS1-associated protein X-1

1

4

High-throughput

0.437

High

276067

NIPS2
Protein NipSnap homolog 2

1

2

Small-scale

0.437

High

352996

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

451335

NFM
Neurofilament medium polypeptide

1

1

High-throughput

0.437

High

697445

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

697504

TNAP2
Tumor necrosis factor alpha-induced protein 2

1

1

Small-scale

0.437

High

697553

ANR55
Ankyrin repeat domain-containing protein 55

1

2

High-throughput

0.437

High

697555

TM41B
Transmembrane protein 41B

1

1

High-throughput

0.437

High

697560

OTUD1
OTU domain-containing protein 1

1

1

High-throughput

0.437

High

697564

FBX42
F-box only protein 42

1

6

High-throughput

0.437

High

697568

LRC31
Leucine-rich repeat-containing protein 31

1

1

High-throughput

0.437

High

697573

KCTD9
BTB/POZ domain-containing protein KCTD9

1

7

High-throughput

0.437

High

697583

S15A3
Solute carrier family 15 member 3

1

1

High-throughput

0.437

High

697694

AAR2
Protein AAR2 homolog

1

1

High-throughput

0.437

High

244927

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

344097

PTBP3
Polypyrimidine tract-binding protein 3

1

0

High-throughput

0.426

High

697496

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

0

High-throughput

0.426

High

697665

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

0

Small-scale

0.426

High

216631

HTRA2
Serine protease HTRA2, mitochondrial

1

1

Small-scale

0.408

High

697469

CEBPA
CCAAT/enhancer-binding protein alpha

1

2

High-throughput

0.408

High

74755

B2Y833
TMPRSS2-ERG prostate cancer specific isoform 1

1

1

Small-scale

0.407

High

697617

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

576615

GBRA1
Gamma-aminobutyric acid receptor subunit alpha-1

1

0

High-throughput

0.249

Low

657489

GCSP
Glycine dehydrogenase

1

0

High-throughput

0.249

Low

697531

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

697638

LGR4
Leucine-rich repeat-containing G-protein coupled receptor 4

1

0

High-throughput

0.249

Low

936

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.232

Low

697566

LRFN4
Leucine-rich repeat and fibronectin type-III domain-containing protein 4

1

0

Small-scale

0.232

Low

697594

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025