HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: LIN7C (Q9NUP9)
Protein lin-7 homolog C (Lin-7C) (Mammalian lin-seven protein 3) (MALS-3) (Vertebrate lin-7 homolog 3) (Veli-3)
Gene: LIN7C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29568061
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane GO:0019904 - protein domain specific binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 197
+	Hs
		547035 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SNTB2_HUMAN (61-179): 3e-32: 123: 35.25
+	Hs
		159150 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		547046 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		SNTB1_HUMAN (65-179): 5.68e-31: 119: 35.90
+	Hs
		719635 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		LIN7C_HUMAN (1-197): 1.38e-57: 181: 100.00
+	Hs
		547030 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		158302 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159272 E41L5_HUMAN (5-586): 7.7e-142: 430: 21.28		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		158255 E41L2_HUMAN (2-577): 1.05e-117: 374: 19.70		LIN7A_HUMAN (6-194): 4.87e-51: 166: 80.42
+	Hs
		159142 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Hs
		719555 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		LNX1_HUMAN (14-179): 1.21e-17: 82.1: 22.02
+	Hs
		663961 PTN4_HUMAN (4-480): 1.13e-123: 388: 22.20		PTN4_HUMAN (43-187): 5.75e-33: 126: 29.14
+	Hs
		663981 PTN4_HUMAN (4-480): 1.13e-123: 388: 22.20		MPP7_HUMAN (31-188): 6.36e-31: 119: 25.95
+	Dm
		677683 MOEH_DROME (2-586): 8.49e-145: 432: 56.01		DLG1_DROME (57-176): 1.06e-14: 73.6: 28.00
+	Hs
		719554 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		INADL_HUMAN (112-194): 6.16e-11: 62.8: 30.12
+	Hs
		505627 EPB41_HUMAN (3-553): 9.55e-129: 400: 22.99		DLG1_HUMAN (50-178): 8.31e-23: 97.1: 30.60
+	Hs
		159273 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		CSKP_HUMAN (13-194): 1.3e-30: 119: 20.53
+	Mm
		1143533 E41LB_MOUSE (4-412): 4.85e-121: 369: 22.01		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Mm
		1143556 E41L3_MOUSE (2-522): 3.29e-115: 366: 21.48		DLG4_MOUSE (59-195): 8.13e-24: 99.8: 26.76
+	Hs
		1020222 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		PTN13_HUMAN (23-196): 2.66e-14: 72.5: 19.43
+	Hs
		280077 E41LA_HUMAN (1-576): 5.03e-116: 361: 16.47		MPDZ_HUMAN (39-162): 6.77e-13: 68.6: 20.16