HitPredict

Interactor 1: EZRI (P15311)
Ezrin (Cytovillin) (Villin-2) (p81)
Gene: EZR

Interactor 2: ICAM5 (Q9UMF0)
Intercellular adhesion molecule 5 (ICAM-5) (Telencephalin)
Gene: ICAM5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	29568061, unassigned1655
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 924
+	Mm
		640203 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		VCAM1_MOUSE (31-675): 4.22e-85: 290: 18.53
+	Hs
		546923 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		VCAM1_HUMAN (7-421): 4.28e-48: 185: 18.76
+	Hs
		581442 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		VCAM1_HUMAN (7-421): 4.28e-48: 185: 18.76
+	Hs
		81626 B7Z5V2_HUMAN (1-586): 4.12e-153: 452: 94.37		VCAM1_HUMAN (7-421): 4.28e-48: 185: 18.76
+	Hs
		530232 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM2_HUMAN (16-230): 9.2e-28: 115: 35.32
+	Hs
		399964 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM1_HUMAN (121-572): 8.18e-25: 111: 18.93
+	Hs
		546948 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		ICAM3_HUMAN (409-875): 2.84e-21: 100: 16.05
+	Hs
		530235 RADI_HUMAN (1-586): 7.83e-165: 484: 76.28		ICAM2_HUMAN (16-230): 9.2e-28: 115: 35.32
+	Hs
		530234 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM2_HUMAN (16-230): 9.2e-28: 115: 35.32
+	Hs
		546947 EZRI_HUMAN (1-586): 5.67e-178: 517: 100.00		L1CAM_HUMAN (505-783): 9.61e-12: 71.2: 27.62
+	Mm
		640204 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		ICAM2_MOUSE (16-208): 6.46e-24: 104: 36.60
+	Hs
		399982 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM1_HUMAN (121-572): 8.18e-25: 111: 18.93
+	Mm
		530229 RADI_MOUSE (1-586): 1.52e-164: 483: 76.28		ICAM1_MOUSE (317-762): 1.55e-21: 101: 19.48
+	Hs
		640050 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		ICAM3_HUMAN (409-875): 2.84e-21: 100: 16.05
+	Hs
		640132 MOES_HUMAN (1-586): 4.45e-161: 474: 72.70		TITIN_HUMAN (747-910): 1.12e-16: 87.7: 11.35
+	Hs
		234481 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		DSCAM_HUMAN (165-485): 1.21e-14: 80.8: 8.41
+	Dm
		709414 MOEH_DROME (2-586): 8.49e-145: 432: 56.01		FAS2_DROME (421-821): 3.29e-11: 69.3: 22.98
+	Hs
		719447 MERL_HUMAN (2-586): 3.18e-146: 436: 44.37		PGBM_HUMAN (119-256): 2.86e-09: 63.5: 14.49
+	Dm
		65329 MERH_DROME (3-586): 1.08e-131: 400: 40.58		OBSCN_DROME (744-909): 1.35e-13: 77.7: 11.48
+	Dm
		709936 Q9W0R3_DROME (3-516): 4.6e-124: 390: 21.76		FAS2_DROME (421-821): 3.29e-11: 69.3: 22.98