HitPredict

Interactor 1: TCPA (P17987)
T-complex protein 1 subunit alpha (TCP-1-alpha) (CCT-alpha) (Chaperonin containing T-complex polypeptide 1 subunit 1)
Gene: TCP1

Interactor 2: PCGF6 (Q9BYE7)
Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134)
Gene: PCGF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	27705803
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 556 Hs			1 350
+	Hs
		826868 TCPG_HUMAN (5-550): 0: 593: 33.03		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		1306663 TCPH_HUMAN (1-545): 0: 566: 34.84		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		573145 TCPA_HUMAN (1-556): 0: 630: 100.00		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		821399 TCPE_HUMAN (4-530): 0: 550: 31.96		PCGF6_HUMAN (1-350): 1.95e-96: 291: 100.00
+	Hs
		717554 TCPG_HUMAN (5-550): 0: 593: 33.03		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		573341 TCPA_HUMAN (1-556): 0: 630: 100.00		PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73
+	Hs
		718138 TCPH_HUMAN (1-545): 0: 566: 34.84		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		717550 TCPE_HUMAN (4-530): 0: 550: 31.96		BMI1_HUMAN (117-349): 8.67e-71: 225: 34.30
+	Hs
		821235 TCPE_HUMAN (4-530): 0: 550: 31.96		PCGF3_HUMAN (120-341): 3.31e-65: 208: 34.44
+	Hs
		573381 TCPA_HUMAN (1-556): 0: 630: 100.00		COP1_HUMAN (126-321): 3.33e-26: 111: 16.00
+	Hs
		1197585 TCPH_HUMAN (1-545): 0: 566: 34.84		PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73
+	Hs
		821290 TCPE_HUMAN (4-530): 0: 550: 31.96		PCGF5_HUMAN (117-344): 6.93e-50: 169: 31.73
+	At
		660201 TCPA_ARATH (7-541): 0: 579: 66.17		COP1_ARATH (66-323): 1.24e-35: 139: 17.83
+	Hs
		826837 TCPG_HUMAN (5-550): 0: 593: 33.03		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		826781 TCPG_HUMAN (5-550): 0: 593: 33.03		COP1_HUMAN (126-321): 3.33e-26: 111: 16.00
+	Hs
		1246158 TCPH_HUMAN (1-545): 0: 566: 34.84		COP1_HUMAN (126-321): 3.33e-26: 111: 16.00
+	Hs
		821376 TCPE_HUMAN (4-530): 0: 550: 31.96		RING2_HUMAN (85-303): 3.51e-32: 124: 14.49
+	Hs
		282573 TCPE_HUMAN (4-530): 0: 550: 31.96		RNF8_HUMAN (74-217): 4.44e-28: 115: 24.16
+	Hs
		821324 TCPE_HUMAN (4-530): 0: 550: 31.96		COP1_HUMAN (126-321): 3.33e-26: 111: 16.00