HitPredict

Interactor 1: VATB1 (P15313)
V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1)
Gene: ATP6V1B1

Interactor 2: DMXL1 (Q9Y485)
DmX-like protein 1 (X-like 1 protein)
Gene: DMXL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007035 - vacuolar acidification
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 3027
+	Hs
		597712 VATB2_HUMAN (21-503): 0: 594: 88.61		DMXL1_HUMAN (1-3027): 0: 4293: 100.00
+	Mm
		1162965 VATB1_MOUSE (1-513): 0: 646: 93.76		DMXL1_MOUSE (1-3027): 0: 4129: 89.34
+	Mm
		69660 VATB1_MOUSE (1-513): 0: 646: 93.76		B0V2P5_MOUSE (1-3019): 0: 3735: 54.32
+	Hs
		597684 VATB2_HUMAN (21-503): 0: 594: 88.61		DMXL2_HUMAN (1-3019): 0: 3756: 54.84
+	Hs
		547327 VATB1_HUMAN (1-513): 0: 650: 100.00		GBB1_HUMAN (2869-3008): 2.21e-17: 88.3: 14.29
+	Hs
		415288 ATPB_HUMAN (41-497): 1.42e-158: 463: 23.23		WDR5_HUMAN (2815-3024): 2.77e-55: 199: 15.64
+	Sc
		556142 VATB_YEAST (17-498): 0: 581: 76.97		RAV1_YEAST (2706-2944): 7.38e-11: 70.6: 11.58