HitPredict

Interactor 1: DMD (P11532)
Dystrophin
Gene: DMD

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.717

Property	Details
Experiments	8576247, 28514442, 33961781, 22937058, unassigned3799
Identification Methods	unspecified method, affinity chromatography technology, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016010 - dystrophin-associated glycoprotein complex GO:0032991 - protein-containing complex and 1 others more... GO:0045202 - synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 3685 Hs			1 540
+	Hs
		547444 DMD_HUMAN (1-3685): 0: 1197: 100.00		SNTB1_HUMAN (24-539): 3.07e-150: 443: 55.30
+	Mm
		547373 DMD_MOUSE (1-3685): 0: 1160: 90.29		SNTB2_MOUSE (16-540): 1.18e-161: 471: 95.05
+	Hs
		547440 DMD_HUMAN (1-3685): 0: 1197: 100.00		SNTA1_HUMAN (16-539): 2.89e-141: 419: 45.49
+	Mm
		547391 DMD_MOUSE (1-3685): 0: 1160: 90.29		SNTB1_MOUSE (24-539): 5.36e-148: 437: 54.53
+	Mm
		547368 DMD_MOUSE (1-3685): 0: 1160: 90.29		Q3UVD6_MOUSE (16-539): 1.76e-144: 427: 45.30
+	Mm
		59444 DMD_MOUSE (1-3685): 0: 1160: 90.29		A2AKD7_MOUSE (16-539): 1.4e-144: 427: 45.49
+	Mm
		547372 DMD_MOUSE (1-3685): 0: 1160: 90.29		SNTA1_MOUSE (16-539): 1.81e-141: 419: 45.15
+	Hs
		547492 DMD_HUMAN (1-3685): 0: 1197: 100.00		SNTG2_HUMAN (103-536): 2.42e-110: 340: 24.04
+	Hs
		547490 DMD_HUMAN (1-3685): 0: 1197: 100.00		SNTG1_HUMAN (103-536): 2.68e-108: 334: 22.66
+	Mm
		547389 DMD_MOUSE (1-3685): 0: 1160: 90.29		SNTG2_MOUSE (44-536): 7.95e-114: 350: 22.87
+	Mm
		547390 DMD_MOUSE (1-3685): 0: 1160: 90.29		SNTG1_MOUSE (103-536): 2.25e-105: 327: 22.56
+	Mm
		1222578 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB2_MOUSE (16-540): 1.18e-161: 471: 95.05
+	Mm
		1243132 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTB1_MOUSE (24-539): 5.36e-148: 437: 54.53
+	Hs
		1118430 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTB1_HUMAN (24-539): 3.07e-150: 443: 55.30
+	Mm
		1190948 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		Q3UVD6_MOUSE (16-539): 1.76e-144: 427: 45.30
+	Hs
		1104783 Q14205_HUMAN (2980-3685): 0: 651: 100.00		SNTA1_HUMAN (16-539): 2.89e-141: 419: 45.49
+	Mm
		1243130 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG2_MOUSE (44-536): 7.95e-114: 350: 22.87
+	Mm
		1243131 Q6P6L2_MOUSE (12-762): 0: 664: 55.79		SNTG1_MOUSE (103-536): 2.25e-105: 327: 22.56
+	Mm
		1053201 DRP2_MOUSE (2782-3680): 1.03e-152: 504: 55.16		SNTG2_MOUSE (44-536): 7.95e-114: 350: 22.87
+	Mm
		1053202 DRP2_MOUSE (2782-3680): 1.03e-152: 504: 55.16		SNTG1_MOUSE (103-536): 2.25e-105: 327: 22.56