HitPredict

Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: IL12A (P43431)
Interleukin-12 subunit alpha (IL-12A) (Cytotoxic lymphocyte maturation factor 35 kDa subunit) (CLMF p35) (IL-12 subunit p35)
Gene: IL12A

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.60	0.601

Property	Details
Experiments	15871905, 14568984
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 329 Mm			1 215
+	Hs
		501001 IRF1_HUMAN (1-329): 5.33e-176: 491: 84.50		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667328 IRF9_HUMAN (7-154): 1e-60: 200: 33.97		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667337 IRF4_HUMAN (7-122): 1.03e-55: 189: 42.24		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667329 IRF8_HUMAN (7-271): 1.72e-55: 188: 26.42		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667334 IRF5_HUMAN (2-125): 5.71e-51: 178: 40.95		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667336 IRF3_HUMAN (1-161): 5.39e-50: 173: 27.95		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90
+	Hs
		667338 IRF7_HUMAN (4-111): 8.86e-37: 139: 30.77		IL12A_HUMAN (1-215): 4.97e-113: 323: 58.90