Interactor 1: IRF1 (P15314)
Interferon regulatory factor 1 (IRF-1)
Gene: IRF1

Interactor 2: TLR9 (Q9EQU3)
Toll-like receptor 9 (CD antigen CD289)
Gene: TLR9

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 0.60 0.479

The method score is based on:

Property Details
Experiments 16301648
Identification Methods electrophoretic mobility supershift assay
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0007249 - canonical NF-kappaB signal transduction
GO:0032728 - positive regulation of interferon-beta production
GO:0032735 - positive regulation of interleukin-12 production
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0051607 - defense response to virus
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 329
Mm

1 1032
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Last updated: 15 Jul 2024