Interactor 1: C1TC (P11586)
C-1-tetrahydrofolate synthase, cytoplasmic (C1-THF synthase) (Epididymis secretory sperm binding protein) [Cleaved into: C-1-tetrahydrofolate synthase, cytoplasmic, N-terminally processed] [Includes: Methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5); Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9); Formyltetrahydrofolate synthetase (EC 6.3.4.3)]
Gene: MTHFD1

Interactor 2: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 0.50 0.533

The method score is based on:

Property Details
Experiments 37827155, 24332808
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms -
Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 935
Hs

1 121
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025