HitPredict

Interactor 1: ATF2 (P15336)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Interactor 2: MK01 (P28482)
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)
Gene: MAPK1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.710

The method score is based on:

Property Details
Experiments 31964530, 11865055, 8995385, 7737129, 15192015
Identification Methods affinity chromatography technology, enzymatic study, protein kinase assay
Interaction Type physical association, direct interaction, phosphorylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006974 - DNA damage response
GO:0018107 - peptidyl-threonine phosphorylation
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 505
Hs

1 360
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Last updated: 15 Jul 2024