HitPredict - High confidence protein-protein interactions

Interactor 1: ATF2 (P15336)
Cyclic AMP-dependent transcription factor ATF-2 (cAMP-dependent transcription factor ATF-2) (Activating transcription factor 2) (Cyclic AMP-responsive element-binding protein 2) (CREB-2) (cAMP-responsive element-binding protein 2) (HB16) (cAMP response element-binding protein CRE-BP1)
Gene: ATF2

Interactor 2: CEBPA (P49715)
CCAAT/enhancer-binding protein alpha (C/EBP alpha)
Gene: CEBPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.57	1.00	0.757

Property	Details
Experiments	14734562, 34189442
Identification Methods	two hybrid, proximity labelling technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	bZIP_1~bZIP_2
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific and 12 others more... GO:0001889 - liver development GO:0003700 - DNA-binding transcription factor activity GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0006357 - regulation of transcription by RNA polymerase II GO:0010628 - positive regulation of gene expression GO:0042803 - protein homodimerization activity GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0050872 - white fat cell differentiation GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0090575 - RNA polymerase II transcription regulator complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1	505
Hs

1	358

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Last updated: 15 Jul 2024