HitPredict

Interactor 1: H2B2E (Q16778)
Histone H2B type 2-E (H2B-clustered histone 21) (Histone H2B-GL105) (Histone H2B.q) (H2B/q)
Gene: H2BC21

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.777

Property	Details
Experiments	35271311, 20368734
Identification Methods	affinity chromatography technology, unspecified method, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	BAH~Histone
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 126 Hs			1 1689
+	Hs
		918481 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		707673 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		PB1_HUMAN (1-1689): 0: 1223: 100.00
+	Hs
		641186 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Hs
		641256 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Hs
		641157 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Xl
		355250 H2B11_XENLA (1-126): 6.19e-53: 164: 94.44		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		1087293 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		918554 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		1066994 H2B2F_HUMAN (1-126): 2.34e-54: 168: 97.62		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		918378 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		707639 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Hs
		631389 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		631445 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		631358 H2B1B_HUMAN (1-126): 1.74e-53: 165: 98.41		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Hs
		918674 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55
+	Hs
		1231243 H2B3B_HUMAN (1-126): 1.01e-51: 161: 96.03		BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55
+	Hs
		1274453 H2B1H_HUMAN (1-126): 6.27e-54: 166: 98.41		ASH1L_HUMAN (535-651): 1.26e-11: 72.4: 29.92
+	Hs
		846915 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		846990 H2B2E_HUMAN (1-126): 6.69e-54: 166: 100.00		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Hs
		846736 H2B1C_HUMAN (1-126): 1.18e-53: 166: 99.21		SMCA2_HUMAN (794-881): 2.15e-09: 64.9: 26.09