Interactor 1: NDKA (P15531)
Nucleoside diphosphate kinase A (NDK A) (NDP kinase A) (EC 2.7.4.6) (Granzyme A-activated DNase) (GAAD) (Metastasis inhibition factor nm23) (NM23-H1) (Tumor metastatic process-associated protein)
Gene: NME1

Interactor 2: NDK3 (Q13232)
Nucleoside diphosphate kinase 3 (NDK 3) (NDP kinase 3) (EC 2.7.4.6) (DR-nm23) (Nucleoside diphosphate kinase C) (NDPKC) (nm23-H3)
Gene: NME3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.954

The method score is based on:

Property Details
Experiments 25416956, 16189514, 28514442, 33961781, 11042679, 31515488
Identification Methods two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains NDK~NDK
Common GO terms GO:0004550 - nucleoside diphosphate kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0006183 - GTP biosynthetic process
and 3 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 152
Hs

1 169
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024