HitPredict

Interactor 1: GNS (P15586)
N-acetylglucosamine-6-sulfatase (EC 3.1.6.14) (Glucosamine-6-sulfatase) (G6S)
Gene: GNS

Interactor 2: FBX6 (Q9NRD1)
F-box only protein 6 (F-box protein that recognizes sugar chains 2) (F-box/G-domain protein 2)
Gene: FBXO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.50	0.533

Property	Details
Experiments	30833792, 22268729
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 552 Hs			1 293
+	Hs
		549108 GNS_HUMAN (1-552): 0: 703: 100.00		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		849848 SPHM_HUMAN (19-521): 1.03e-109: 338: 21.17		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1165670 ARSK_HUMAN (43-510): 8.62e-108: 334: 21.37		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		99729 F5H4C6_HUMAN (78-323): 1.81e-96: 295: 100.00		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		550480 ARSB_HUMAN (35-533): 9.78e-115: 352: 17.28		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		849851 SPHM_HUMAN (19-521): 1.03e-109: 338: 21.17		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1165674 ARSK_HUMAN (43-510): 8.62e-108: 334: 21.37		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1219531 SULF2_HUMAN (430-523): 9.95e-23: 104: 33.67		FBX6_HUMAN (1-293): 1.15e-178: 495: 100.00
+	Hs
		1219541 SULF2_HUMAN (430-523): 9.95e-23: 104: 33.67		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17
+	Hs
		1219555 SULF1_HUMAN (430-522): 1.9e-22: 103: 30.93		FBX2_HUMAN (23-259): 3.78e-119: 345: 49.17