Protein: CDK1
Cyclin-dependent kinase 1 (CDK1) (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 homolog) (Cell division protein kinase 1) (p34 protein kinase)

Gene: CDK1
Organism: Mus musculus
Interactions: 39
UniProt ID: P11440

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000086 - G2/M transition of mitotic cell cycle
GO:0003682 - chromatin binding
GO:0004672 - protein kinase activity
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

543009

CCNB1
G2/mitotic-specific cyclin-B1

7

20

Small-scale

0.961

High

543020

CCNA2
Cyclin-A2

2

20

Small-scale

0.806

High

543029

CCNE1
G1/S-specific cyclin-E1

2

20

Small-scale

0.754

High

543016

H11
Histone H1.1

3

18

Small-scale

0.655

High

543018

CDK5
Cyclin-dependent kinase 5

1

17

Small-scale

0.647

High

543007

PO5F1
POU domain, class 5, transcription factor 1

2

5

Small-scale

0.639

High

543006

HSP72
Heat shock-related 70 kDa protein 2

2

4

Small-scale

0.624

High

543010

CCND1
G1/S-specific cyclin-D1

1

20

Small-scale

0.618

High

543011

BRAF
Serine/threonine-protein kinase B-raf

1

11

High-throughput

0.618

High

543012

CCND2
G1/S-specific cyclin-D2

1

20

Small-scale

0.618

High

543014

CDN1A
Cyclin-dependent kinase inhibitor 1

1

20

Small-scale

0.618

High

543017

MPIP3
M-phase inducer phosphatase 3

1

18

Small-scale

0.618

High

543031

CCNC
Cyclin-C

1

20

Small-scale

0.618

High

543036

ZN281
Zinc finger protein 281

1

1

Small-scale

0.618

High

543004

H12
Histone H1.2

2

18

Small-scale

0.602

High

543038

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

2

4

Small-scale

0.571

High

543037

NASP
Nuclear autoantigenic sperm protein

1

2

Small-scale

0.561

High

543022

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

13

High-throughput

0.515

High

534007

H10
Histone H1.0

1

7

Small-scale

0.501

High

543015

PURA
Transcriptional activator protein Pur-alpha

1

1

Small-scale

0.501

High

543023

H32
Histone H3.2

1

2

Small-scale

0.501

High

543025

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

2

Small-scale

0.501

High

518498

MYOD1
Myoblast determination protein 1

1

0

Small-scale

0.480

High

543008

MDM2
E3 ubiquitin-protein ligase Mdm2

1

1

Small-scale

0.479

High

543021

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

Small-scale

0.479

High

543024

FHL1
Four and a half LIM domains protein 1

1

1

Small-scale

0.479

High

543030

ERR2
Steroid hormone receptor ERR2

1

5

High-throughput

0.479

High

543034

EED
Polycomb protein EED

1

7

High-throughput

0.479

High

543027

STING
Stimulator of interferon genes protein

1

0

High-throughput

0.458

High

543032

FACD2
Fanconi anemia group D2 protein homolog

1

0

High-throughput

0.458

High

543013

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

2

High-throughput

0.445

High

543033

E2F4
Transcription factor E2F4

1

14

High-throughput

0.445

High

543035

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

6

Small-scale

0.445

High

237127

IMPCT
Protein IMPACT

1

1

Small-scale

0.437

High

543005

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.437

High

543026

TRI72
Tripartite motif-containing protein 72

1

3

Small-scale

0.437

High

543028

CLU
Clustered mitochondria protein homolog

1

3

High-throughput

0.437

High

399476

GFAP
Glial fibrillary acidic protein

1

3

High-throughput

0.407

High

543019

ADT2
ADP/ATP translocase 2

1

2

High-throughput

0.407

High


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Last updated: 11Aug2025