Interactor 1: SYFB (P15624)
Phenylalanine--tRNA ligase beta subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase beta subunit) (PheRS)
Gene: FRS1

Interactor 2: SYFA (P15625)
Phenylalanine--tRNA ligase alpha subunit (EC 6.1.1.20) (Phenylalanyl-tRNA synthetase alpha subunit) (PheRS)
Gene: FRS2

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 1.00 0.896

The method score is based on:

Property Details
Experiments 11805826, 16429126, 16554755, 37968396
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains B3_4~tRNA-synt_2d, B5~tRNA-synt_2d, PhetRS_B1~tRNA-synt_2d, tRNA-synt_2d~tRNA_synthFbeta
Common GO terms GO:0000287 - magnesium ion binding
GO:0004826 - phenylalanine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0006432 - phenylalanyl-tRNA aminoacylation
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 595
Sc

1 503
+ Hs
+ Dm
+ Ce
+ Mt
+ Ec
+ Nv
+ Tt
+ Mp

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Last updated: 15 Jul 2024