Interactor 1: PUR9 (P15639)
Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]
Gene: purH
Interactor 2: PUR9 (P15639)
Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase (EC 2.1.2.3) (AICAR transformylase); IMP cyclohydrolase (EC 3.5.4.10) (ATIC) (IMP synthase) (Inosinicase)]
Gene: purH
Species: Escherichia coli K-12
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.48 | 1.00 | 0.698 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 24561554 |
| Identification Methods | two hybrid, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | AICARFT_IMPCHas~AICARFT_IMPCHas, AICARFT_IMPCHas~MGS, MGS~MGS |
| Common GO terms | GO:0003937 - IMP cyclohydrolase activity GO:0004643 - phosphoribosylaminoimidazolecarboxamide formyltransferase activity GO:0005829 - cytosol GO:0006189 - 'de novo' IMP biosynthetic process |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
