Interactor 1: VEGFA (P15692)
Vascular endothelial growth factor A, long form (L-VEGF) (Vascular permeability factor) (VPF) [Cleaved into: N-VEGF; VEGFA]
Gene: VEGFA

Interactor 2: PGBM (P98160)
Basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) (Perlecan) (PLC) [Cleaved into: Endorepellin; LG3 peptide]
Gene: HSPG2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 19422911
Identification Methods far western blotting
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_3~PDGF
Common GO terms GO:0001525 - angiogenesis
GO:0001666 - response to hypoxia
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005576 - extracellular region
GO:0005615 - extracellular space
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 395
Hs

1 4391
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024