HitPredict

Interactor 1: UBC4 (P15731)
Ubiquitin-conjugating enzyme E2 4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein 4) (Ubiquitin-protein ligase 4)
Gene: UBC4

Interactor 2: PEX10 (Q05568)
Peroxisome biogenesis factor 10 (EC 2.3.2.27) (Peroxin-10) (Peroxisomal biogenesis factor 10) (Peroxisome assembly protein 10)
Gene: PEX10

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.778

Property	Details
Experiments	22471590, 24034674
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0000209 - protein polyubiquitination GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 148 Sc			1 337
+	Hs
		256237 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		BRE1B_HUMAN (1-336): 1.06e-38: 148: 11.73
+	Hs
		282581 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RNF8_HUMAN (2-331): 3.03e-37: 140: 13.78
+	Hs
		282607 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RNF8_HUMAN (2-331): 3.03e-37: 140: 13.78
+	Hs
		919748 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		BRE1A_HUMAN (1-336): 2.07e-35: 138: 13.68
+	Hs
		1170316 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		ARK2C_HUMAN (104-330): 5.09e-26: 107: 16.52
+	Hs
		1356614 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		AMFR_HUMAN (180-337): 2.15e-24: 105: 16.98
+	Hs
		849350 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		ARK2C_HUMAN (104-330): 5.09e-26: 107: 16.52
+	Hs
		1292368 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		RN185_HUMAN (276-336): 5.51e-26: 104: 31.25
+	Hs
		919759 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		ARK2C_HUMAN (104-330): 5.09e-26: 107: 16.52
+	Hs
		849484 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		AMFR_HUMAN (180-337): 2.15e-24: 105: 16.98
+	Hs
		1307272 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		RNF5_HUMAN (262-336): 1.79e-25: 102: 26.92
+	Hs
		849409 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RN185_HUMAN (276-336): 5.51e-26: 104: 31.25
+	Hs
		919826 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RN185_HUMAN (276-336): 5.51e-26: 104: 31.25
+	Hs
		849424 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RNF5_HUMAN (262-336): 1.79e-25: 102: 26.92
+	Hs
		919838 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RNF5_HUMAN (262-336): 1.79e-25: 102: 26.92
+	At
		715141 UBC9_ARATH (2-148): 2.68e-82: 240: 76.87		Q9LN67_ARATH (284-336): 3.86e-24: 100: 33.93
+	Hs
		919736 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RN151_HUMAN (272-335): 1.5e-21: 93.5: 26.56
+	Hs
		1290204 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		RN125_HUMAN (260-332): 4.07e-19: 86.6: 25.68
+	Hs
		849405 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RN125_HUMAN (260-332): 4.07e-19: 86.6: 25.68
+	Hs
		919821 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RN125_HUMAN (260-332): 4.07e-19: 86.6: 25.68