HitPredict

Interactor 1: UBC4 (P15731)
Ubiquitin-conjugating enzyme E2 4 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein 4) (Ubiquitin-protein ligase 4)
Gene: UBC4

Interactor 2: APC11 (Q12157)
Anaphase-promoting complex subunit 11 (EC 6.3.2.-)
Gene: APC11

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.97	1.00	0.988

Property	Details
Experiments	10888670, 19475395, 12574115, 16364911, 23707760, 17632060, 25217616, 23049888, 15797379, 23751495, 21460798, 25877870, 26573515, 26306044, 17889668, 21562221, 18498748, 22079111, 23078409, 22940250 and 1 others more... 17018280
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-ANAPC11
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 148 Sc			1 165
+	Sc
		549868 UBC5_YEAST (1-148): 6.96e-82: 239: 92.57		APC11_YEAST (1-165): 1.27e-93: 270: 100.00
+	Hs
		849463 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		919882 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		895932 UB2D3_HUMAN (2-148): 4.59e-81: 236: 78.91		APC11_HUMAN (1-102): 6.93e-34: 116: 41.18
+	Hs
		921482 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Sp
		804461 UBC4_SCHPO (2-148): 1.77e-80: 235: 82.31		APC11_SCHPO (1-101): 1.32e-32: 113: 45.55
+	Hs
		849303 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		895979 UB2D1_MOUSE (2-148): 1.97e-82: 240: 78.23		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Hs
		919703 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		919923 UB2D2_MOUSE (2-148): 3.09e-82: 239: 78.91		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Ce
		715108 UBC2_CAEEL (2-148): 4.06e-82: 239: 78.23		APC11_CAEEL (1-102): 6.48e-29: 105: 36.54
+	Ce
		715111 UBC2_CAEEL (2-148): 4.06e-82: 239: 78.23		RBX1_CAEEL (2-102): 2.7e-29: 105: 27.36
+	Hs
		895771 UB2D3_HUMAN (2-148): 4.59e-81: 236: 78.91		RBX1_HUMAN (2-102): 1.24e-30: 108: 26.42
+	Mm
		895973 UB2D3_MOUSE (2-148): 4.59e-81: 236: 78.91		RBX1_MOUSE (2-102): 1.24e-30: 108: 26.42
+	Sc
		549843 UBC4_YEAST (1-148): 2.13e-82: 240: 100.00		RBX1_YEAST (2-102): 9.21e-26: 96.8: 27.36
+	Sc
		549867 UBC5_YEAST (1-148): 6.96e-82: 239: 92.57		RBX1_YEAST (2-102): 9.21e-26: 96.8: 27.36
+	Hs
		1354003 UB2D4_HUMAN (2-148): 4.02e-83: 242: 79.59		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		849472 UB2D1_HUMAN (2-148): 1.97e-82: 240: 78.23		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		919890 UB2D2_HUMAN (2-148): 3.09e-82: 239: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51
+	Hs
		895936 UB2D3_HUMAN (2-148): 4.59e-81: 236: 78.91		RBX2_HUMAN (3-102): 4.14e-24: 92.2: 24.51