HitPredict

Interactor 1: ZEP1 (P15822)
Zinc finger protein 40 (Cirhin interaction protein) (CIRIP) (Gate keeper of apoptosis-activating protein) (GAAP) (Human immunodeficiency virus type I enhancer-binding protein 1) (HIV-EP1) (Major histocompatibility complex-binding protein 1) (MBP-1) (Positive regulatory domain II-binding factor 1) (PRDII-BF1)
Gene: HIVEP1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.89	0.60	0.732

Property	Details
Experiments	25332235, 25900982, 26091241, 28514442, 33961781, 19615732
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2718 Hs			1 605
+	Hs
		681187 ZEP2_HUMAN (332-2324): 0: 1190: 29.76		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		681186 ZEP2_HUMAN (332-2324): 0: 1190: 29.76		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		550444 ZEP1_HUMAN (2-2718): 0: 801: 100.00		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1033684 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		POC1B_HUMAN (189-438): 4.67e-35: 140: 13.27
+	Hs
		1163022 ZN764_HUMAN (389-457): 7.59e-11: 68.8: 37.68		TRAF7_HUMAN (416-589): 7.75e-29: 123: 27.12
+	Hs
		1033727 IKZF1_HUMAN (2001-2144): 1.33e-11: 71.9: 28.77		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67
+	Hs
		1318186 IKZF3_HUMAN (358-457): 1.52e-11: 71.9: 35.00		TBL1R_HUMAN (501-605): 3.85e-15: 80.4: 16.67