HitPredict

Interactor 1: CHIN (P15882)
N-chimaerin (A-chimaerin) (Alpha-chimerin) (N-chimerin) (NC) (Rho GTPase-activating protein 2)
Gene: CHN1

Interactor 2: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	32203420
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	C1_1~Ras, Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0008045 - motor neuron axon guidance
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 459 Hs			1 192
+	Hs
		856140 CHIO_HUMAN (7-459): 1.14e-160: 463: 73.51		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Mm
		925802 CHIO_MOUSE (182-459): 4.8e-104: 314: 76.98		RAC1_MOUSE (1-192): 3.81e-86: 253: 100.00
+	Ce
		983038 Q965N4_CAEEL (16-454): 1.68e-111: 336: 35.89		CDC42_CAEEL (1-192): 5.89e-76: 227: 69.27
+	Hs
		925599 RGAP1_HUMAN (50-453): 5.41e-83: 269: 24.10		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		63073 RHG42_HUMAN (48-459): 8.24e-80: 266: 21.67		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		63065 RHG42_HUMAN (48-459): 8.24e-80: 266: 21.67		RAC2_HUMAN (1-192): 1.2e-82: 244: 92.19
+	Hs
		892584 RGAP1_HUMAN (50-453): 5.41e-83: 269: 24.10		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		63072 RHG42_HUMAN (48-459): 8.24e-80: 266: 21.67		RAC3_HUMAN (1-191): 2.72e-79: 236: 93.19
+	Hs
		436497 RGAP1_HUMAN (50-453): 5.41e-83: 269: 24.10		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		925378 RHG27_HUMAN (114-459): 8.55e-69: 237: 24.15		RAC1_HUMAN (1-192): 3.81e-86: 253: 100.00
+	Hs
		893974 MYO9B_HUMAN (25-455): 3.67e-73: 252: 19.64		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Sp
		251348 RGA4_SCHPO (15-459): 2.23e-70: 242: 20.21		CDC42_SCHPO (1-192): 9.82e-82: 242: 68.23
+	Hs
		70662 MYO9A_HUMAN (23-455): 4.77e-72: 249: 22.10		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		900443 MYO9B_HUMAN (25-455): 3.67e-73: 252: 19.64		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		70663 MYO9A_HUMAN (23-455): 4.77e-72: 249: 22.10		RHOA_HUMAN (5-192): 3.5e-77: 230: 57.98
+	Hs
		436289 MYO9B_HUMAN (25-455): 3.67e-73: 252: 19.64		RHOC_HUMAN (5-192): 8.68e-75: 224: 57.45
+	Hs
		894152 RHG27_HUMAN (114-459): 8.55e-69: 237: 24.15		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Hs
		894533 GMIP_HUMAN (190-459): 2.96e-68: 236: 30.10		CDC42_HUMAN (1-192): 1.4e-78: 234: 70.31
+	Ce
		93900 F0IWT2_CAEEL (32-454): 8.72e-68: 237: 18.24		CDC42_CAEEL (1-192): 5.89e-76: 227: 69.27
+	Ce
		93901 F0IWT2_CAEEL (32-454): 8.72e-68: 237: 18.24		RHO1_CAEEL (5-192): 4.91e-75: 225: 59.04