Protein: OBSCN
Obscurin (EC 2.7.11.1) (Obscurin-RhoGEF) (Obscurin-myosin light chain kinase) (Obscurin-MLCK)

Gene: OBSCN
Organism: Homo sapiens
Interactions: 63
UniProt ID: Q5VST9

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1217422

TITIN
Titin

5

18

Small-scale

0.944

High

592939

ANK1
Ankyrin-1

4

7

Small-scale

0.908

High

541542

FGFR1
Fibroblast growth factor receptor 1

2

13

High-throughput

0.737

High

298925

DNJB5
DnaJ homolog subfamily B member 5

1

7

High-throughput

0.698

High

996982

TBA4A
Tubulin alpha-4A chain

1

6

High-throughput

0.691

High

1120194

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

14

High-throughput

0.691

High

1217414

TBA1A
Tubulin alpha-1A chain

1

7

High-throughput

0.691

High

1217416

MLKL
Mixed lineage kinase domain-like protein

1

2

High-throughput

0.691

High

1217420

BRSK1
Serine/threonine-protein kinase BRSK1

1

14

High-throughput

0.691

High

799200

BRCA1
Breast cancer type 1 susceptibility protein

1

9

High-throughput

0.621

High

1030655

ANK2
Ankyrin-2

1

7

Small-scale

0.618

High

975739

RL7A
Large ribosomal subunit protein eL8

2

2

High-throughput

0.584

High

1217433

RL36
Large ribosomal subunit protein eL36

2

0

High-throughput

0.559

High

1217413

WDR82
WD repeat-containing protein 82

1

13

High-throughput

0.553

High

1217419

POC1B
POC1 centriolar protein homolog B

1

8

High-throughput

0.553

High

483348

CLCB
Clathrin light chain B

1

2

High-throughput

0.536

High

551092

PCNA
Proliferating cell nuclear antigen

1

2

High-throughput

0.536

High

565633

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

1

High-throughput

0.536

High

844796

EAA1
Excitatory amino acid transporter 1

1

1

High-throughput

0.536

High

1116492

FHL3
Four and a half LIM domains protein 3

1

13

High-throughput

0.536

High

1206978

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

1

High-throughput

0.536

High

1217412

LYPD4
Ly6/PLAUR domain-containing protein 4

1

1

High-throughput

0.536

High

1217429

SHLB2
Endophilin-B2

1

4

High-throughput

0.536

High

408922

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.515

High

1105033

TCOF
Treacle protein

1

16

High-throughput

0.515

High

1162974

H2B2E
Histone H2B type 2-E

1

13

High-throughput

0.515

High

1217423

ESR2
Estrogen receptor beta

1

10

High-throughput

0.514

High

927348

ATX1
Ataxin-1

1

0

High-throughput

0.513

High

1217415

MON2
Protein MON2 homolog

1

0

High-throughput

0.513

High

1217424

CDCA5
Sororin

1

0

High-throughput

0.513

High

1217431

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.513

High

988998

AP2B1
AP-2 complex subunit beta

1

4

High-throughput

0.501

High

695673

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.489

High

1217426

DIDO1
Death-inducer obliterator 1

1

12

High-throughput

0.489

High

535166

BIP
Endoplasmic reticulum chaperone BiP

1

3

High-throughput

0.479

High

859625

RL21
Large ribosomal subunit protein eL21

1

1

High-throughput

0.479

High

880320

RL34
Large ribosomal subunit protein eL34

1

1

High-throughput

0.479

High

884348

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

5

High-throughput

0.479

High

929970

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

960140

RL26
Large ribosomal subunit protein uL24

1

2

High-throughput

0.479

High

1102568

MTA1
Metastasis-associated protein MTA1

1

3

High-throughput

0.479

High

1161488

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1217408

RN123
E3 ubiquitin-protein ligase RNF123

1

10

High-throughput

0.479

High

1217409

DCA15
DDB1- and CUL4-associated factor 15

1

1

High-throughput

0.479

High

1217410

RNF43
E3 ubiquitin-protein ligase RNF43

1

3

High-throughput

0.479

High

1217417

KCTD6
BTB/POZ domain-containing protein KCTD6

1

7

Small-scale

0.479

High

1217418

FBX22
F-box only protein 22

1

1

High-throughput

0.479

High

1217421

NUDC2
NudC domain-containing protein 2

1

2

High-throughput

0.479

High

711646

3MG
DNA-3-methyladenine glycosylase

1

0

Small-scale

0.458

High

372262

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.445

High

1114881

CUL4A
Cullin-4A

1

16

High-throughput

0.437

High

1217407

BTBD8
BTB/POZ domain-containing protein 8

1

13

High-throughput

0.407

High

1217432

RT23
Small ribosomal subunit protein mS23

1

1

High-throughput

0.407

High

376992

ANF
Natriuretic peptides A

1

0

High-throughput

0.279

Low

424418

HMGN1
Non-histone chromosomal protein HMG-14

1

0

High-throughput

0.279

Low

480178

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.279

Low

1044349

HSF2
Heat shock factor protein 2

1

0

High-throughput

0.279

Low

1149580

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.279

Low

1217411

HEAT6
HEAT repeat-containing protein 6

1

0

High-throughput

0.279

Low

1217430

VPS18
Vacuolar protein sorting-associated protein 18 homolog

1

0

High-throughput

0.279

Low

1217427

ALG2
Alpha-1,3/1,6-mannosyltransferase ALG2

1

0

High-throughput

0.249

Low

1217428

MRM3
rRNA methyltransferase 3, mitochondrial

1

0

High-throughput

0.249

Low

1217425

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025