Interactor 1: ITF2 (P15884)
Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: TCF4

Interactor 2: CTNB1 (P35222)
Catenin beta-1 (Beta-catenin)
Gene: CTNNB1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.771

The method score is based on:

Property Details
Experiments 24532795, 15060161, 17962194, 15665104, 21743491, 15331612, 28829046, 17220880, 29374067, 26123998, 30691485, 29463646, 11713476, 22014570, 26122848, 24846398, 17412698, 18281465, 15525529, 23449499 and 22 others

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Identification Methods affinity chromatography technology, pull down, x-ray crystallography, two hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005667 - transcription regulator complex
GO:0045893 - positive regulation of DNA-templated transcription
GO:0045944 - positive regulation of transcription by RNA polymerase II
GO:0070369 - beta-catenin-TCF7L2 complex
and 1 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 667
Hs

1 781
+ Mm
+ Xl
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024