HitPredict

Interactor 1: ITF2 (P15884)
Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: TCF4

Interactor 2: HEN1 (Q02575)
Helix-loop-helix protein 1 (HEN-1) (Class A basic helix-loop-helix protein 35) (bHLHa35) (Nescient helix loop helix 1) (NSCL-1)
Gene: NHLH1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 35140242
Identification Methods proximity labelling technology, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains HLH~HLH
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0005634 - nucleus
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 667
Hs

1 133
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024