HitPredict

Interactor 1: ITF2 (P15884)
Transcription factor 4 (TCF-4) (Class B basic helix-loop-helix protein 19) (bHLHb19) (Immunoglobulin transcription factor 2) (ITF-2) (SL3-3 enhancer factor 2) (SEF-2)
Gene: TCF4

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005667 - transcription regulator complex
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 667 Hs			1 197
+	Hs
		551124 ITF2_HUMAN (1-667): 0: 908: 100.00		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		551125 ITF2_HUMAN (1-667): 0: 908: 100.00		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		980851 HTF4_HUMAN (3-667): 0: 783: 61.71		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		551506 TFE2_HUMAN (1-667): 0: 733: 49.71		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		551507 TFE2_HUMAN (1-667): 0: 733: 49.71		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50