HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: NCK1 (P16333)
SH2/SH3 adapter protein NCK1 (Cytoplasmic protein NCK1) (NCK adapter protein 1) (Nck-1) (SH2/SH3 adapter protein NCK-alpha)
Gene: NCK1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1043 Hs			1 377
+	Hs
		557799 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		NCK1_HUMAN (1-377): 1.69e-98: 299: 100.00
+	Hs
		208986 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24
+	Hs
		209122 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		NCK2_HUMAN (1-376): 7.1e-90: 277: 68.24
+	Hs
		411977 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		442773 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		HCK_HUMAN (2-174): 4.07e-20: 93.7: 17.24
+	Hs
		412363 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		523138 TRIM7_HUMAN (288-563): 3.13e-38: 152: 16.83		SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32
+	Hs
		536781 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		412424 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		FYN_HUMAN (7-173): 7.47e-21: 96: 15.39
+	Hs
		924879 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Hs
		1331810 RNF41_HUMAN (283-468): 1.49e-37: 145: 20.00		ITSN2_HUMAN (7-85): 2.68e-12: 70.6: 24.05
+	Mm
		403426 TRAF6_MOUSE (281-451): 5.96e-31: 130: 20.12		SRC_MOUSE (5-114): 1.55e-15: 79.7: 22.32
+	Hs
		523227 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32
+	Hs
		523076 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		SRC_HUMAN (5-114): 1.61e-15: 79.7: 22.32
+	Hs
		924718 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		GRB2_HUMAN (3-61): 2.12e-16: 79.1: 28.81
+	Mm
		936290 TRAF6_MOUSE (281-451): 5.96e-31: 130: 20.12		VAV3_MOUSE (1-58): 6.06e-12: 69: 24.59
+	Hs
		1356641 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		VAV3_HUMAN (1-58): 1.16e-12: 71.4: 24.59
+	Hs
		782838 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		CSK_HUMAN (4-143): 1.92e-12: 70.2: 14.38
+	Hs
		433514 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		YES_HUMAN (112-218): 4.18e-11: 66.1: 19.27
+	Hs
		433465 TRIM5_HUMAN (71-272): 6.46e-16: 84.1: 10.63		YES_HUMAN (112-218): 4.18e-11: 66.1: 19.27