Protein: MYO5
Myosin-5 (Actin-dependent myosin-I MYO5) (Class I unconventional myosin MYO5) (Type I myosin MYO5)

Gene: MYO5
Organism: Saccharomyces cerevisiae S288C
Interactions: 136
UniProt ID: Q04439

Gene Ontology (top 5):
GO:0000146 - microfilament motor activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005933 - cellular bud

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

420336

CALM
Calmodulin

8

20

Small-scale

0.977

High

811145

BBC1
Myosin tail region-interacting protein MTI1

5

8

Small-scale

0.944

High

979584

OSH2
Oxysterol-binding protein homolog 2

5

3

Small-scale

0.939

High

979566

MYO5
Myosin-5

5

17

Small-scale

0.934

High

764132

RV167
Reduced viability upon starvation protein 167

5

13

Small-scale

0.925

High

689378

ARP2
Actin-related protein 2

4

20

Small-scale

0.891

High

730593

MYO3
Myosin-3

3

19

High-throughput

0.868

High

755666

BZZ1
Protein BZZ1

3

5

High-throughput

0.867

High

811962

ARP3
Actin-related protein 3

3

20

Small-scale

0.849

High

887671

ACT
Actin

2

17

Small-scale

0.821

High

819908

CLA4
Serine/threonine-protein kinase CLA4

2

20

High-throughput

0.807

High

698000

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

2

6

High-throughput

0.793

High

858853

YGZ2
Ankyrin repeat-containing protein YGL242C

3

15

High-throughput

0.765

High

741558

VRP1
Verprolin

12

7

Small-scale

0.763

High

979583

LAS17
Proline-rich protein LAS17

9

8

Small-scale

0.757

High

748555

ARPC1
Actin-related protein 2/3 complex subunit 1

5

18

Small-scale

0.715

High

551390

ABP1
Actin-binding protein

2

15

Small-scale

0.712

High

698116

YSC84
Protein YSC84

1

11

High-throughput

0.698

High

797850

LSB3
LAS seventeen-binding protein 3

1

16

High-throughput

0.698

High

703308

ARPC4
Actin-related protein 2/3 complex subunit 4

4

3

Small-scale

0.680

High

773872

BNR1
BNI1-related protein 1

3

7

High-throughput

0.674

High

964729

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

3

20

High-throughput

0.674

High

773905

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

3

15

High-throughput

0.671

High

847143

SHE4
SWI5-dependent HO expression protein 4

3

1

Small-scale

0.670

High

959818

2ABA
Protein phosphatase PP2A regulatory subunit B

3

1

High-throughput

0.666

High

775033

ARPC5
Actin-related protein 2/3 complex subunit 5

3

5

Small-scale

0.658

High

979569

ARPC3
Actin-related protein 2/3 complex subunit 3

3

4

Small-scale

0.658

High

492366

HSP71
Heat shock protein SSA1

3

7

High-throughput

0.656

High

753647

HSE1
Class E vacuolar protein-sorting machinery protein HSE1

1

12

High-throughput

0.625

High

494904

HSP72
Heat shock protein SSA2

3

7

High-throughput

0.624

High

767916

SHO1
High osmolarity signaling protein SHO1

1

0

High-throughput

0.622

High

979573

SRL1
Cell wall protein SRL1

2

1

High-throughput

0.620

High

975910

PKH3
Serine/threonine-protein kinase PKH3

2

19

High-throughput

0.619

High

767037

ZRG8
Zinc-regulated protein 8

2

1

High-throughput

0.602

High

775608

AIM21
Altered inheritance of mitochondria protein 21

2

4

High-throughput

0.602

High

979586

SKM1
Serine/threonine-protein kinase SKM1

1

20

High-throughput

0.590

High

866342

APP1
Phosphatidate phosphatase APP1

2

1

High-throughput

0.586

High

864464

ARPC2
Actin-related protein 2/3 complex subunit 2

2

3

Small-scale

0.584

High

765591

SAP1
Protein SAP1

1

2

High-throughput

0.578

High

692248

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

7

Small-scale

0.573

High

512648

SSB1
Ribosome-associated molecular chaperone SSB1

2

7

High-throughput

0.571

High

753082

OSH3
Oxysterol-binding protein homolog 3

1

3

Small-scale

0.552

High

976584

STE20
Serine/threonine-protein kinase STE20

1

20

High-throughput

0.552

High

979574

YO389
Uncharacterized protein YOR389W

2

3

High-throughput

0.550

High

602755

MCK1
Protein kinase MCK1

1

17

High-throughput

0.541

High

635316

SYP1
Suppressor of yeast profilin deletion

1

10

High-throughput

0.541

High

682294

ACBP
Acyl-CoA-binding protein

1

1

High-throughput

0.541

High

731438

MID2
Cell wall integrity sensor MID2

1

5

High-throughput

0.541

High

837171

HSV2
SVP1-like protein 2

1

4

High-throughput

0.541

High

859016

MCM6
DNA replication licensing factor MCM6

1

9

High-throughput

0.541

High

872872

ZDS2
Protein ZDS2

1

3

High-throughput

0.541

High

962628

ACAC
Acetyl-CoA carboxylase

1

1

High-throughput

0.541

High

972674

STD1
Protein STD1

1

3

High-throughput

0.541

High

974453

MET31
Transcriptional regulator MET31

1

1

High-throughput

0.541

High

979568

CYK2
Cytokinesis protein 2

1

6

High-throughput

0.541

High

979579

HER1
HMG2-induced ER-remodeling protein 1

1

6

High-throughput

0.541

High

597896

PWP1
Periodic tryptophan protein 1

1

4

High-throughput

0.536

High

667889

MCM5
Minichromosome maintenance protein 5

1

10

High-throughput

0.536

High

579950

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

11

Small-scale

0.527

High

628442

SIS1
Protein SIS1

2

1

High-throughput

0.521

High

691161

KRE6
Beta-glucan synthesis-associated protein KRE6

1

0

High-throughput

0.518

High

766473

EDC3
Enhancer of mRNA-decapping protein 3

1

0

High-throughput

0.518

High

772403

ATG3
Autophagy-related protein 3

1

0

High-throughput

0.518

High

774714

YIJ2
Uncharacterized protein YIL092W

1

0

High-throughput

0.518

High

792370

YG4I
Uncharacterized GTP-binding protein YGR210C

1

0

High-throughput

0.518

High

979581

SCM3
Protein SCM3

1

0

High-throughput

0.518

High

425382

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

334814

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.508

High

784656

BNI1
Protein BNI1

1

7

High-throughput

0.508

High

626483

ERG6
Sterol 24-C-methyltransferase ERG6

1

3

Small-scale

0.504

High

979585

ERG27
3-keto-steroid reductase ERG27

1

4

Small-scale

0.504

High

704714

PRP8
Pre-mRNA-splicing factor 8

1

1

High-throughput

0.501

High

859049

MDS3
Negative regulator of sporulation MDS3

1

1

High-throughput

0.501

High

978080

VPS64
Vacuolar protein sorting-associated protein 64

1

1

High-throughput

0.501

High

716072

MTH1
Protein MTH1

1

3

High-throughput

0.494

High

814152

SSN8
RNA polymerase II holoenzyme cyclin-like subunit

1

2

High-throughput

0.494

High

804844

RSSA2
Small ribosomal subunit protein uS2B

1

1

High-throughput

0.489

High

976283

PKH1
Serine/threonine-protein kinase PKH1

1

18

Small-scale

0.481

High

979578

PKH2
Serine/threonine-protein kinase PKH2

1

18

Small-scale

0.481

High

713201

SCD5
Protein SCD5

1

0

High-throughput

0.480

High

859630

LSG1
Large subunit GTPase 1

1

0

High-throughput

0.480

High

977836

YD132
Uncharacterized protein YDR132C

1

0

High-throughput

0.480

High

979577

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.480

High

752975

YHI0
Putative proline--tRNA ligase YHR020W

1

3

High-throughput

0.479

High

762536

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.479

High

765059

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.479

High

767972

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

2

Small-scale

0.479

High

979570

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.479

High

343688

PMG1
Phosphoglycerate mutase 1

1

1

High-throughput

0.464

High

626042

MED19
Mediator of RNA polymerase II transcription subunit 19

1

1

High-throughput

0.464

High

733745

SUMT
Uroporphyrinogen-III C-methyltransferase

1

1

High-throughput

0.464

High

615303

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.458

High

701079

SMY2
Protein SMY2

1

0

High-throughput

0.458

High

753946

RPN1
26S proteasome regulatory subunit RPN1

1

0

High-throughput

0.458

High

979575

YP277
Uncharacterized protein YPL277C

1

3

High-throughput

0.457

High

434778

PBS2
MAP kinase kinase PBS2

1

20

High-throughput

0.457

High

653133

MIG1
Regulatory protein MIG1

1

3

High-throughput

0.457

High

679998

2AAA
Protein phosphatase PP2A regulatory subunit A

1

1

High-throughput

0.457

High

867916

MPS1
Serine/threonine-protein kinase MPS1

1

20

High-throughput

0.457

High

368387

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

695479

HSP7F
Heat shock protein homolog SSE1

1

10

High-throughput

0.445

High

705628

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.445

High

769415

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

785205

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.445

High

605261

AFT1
Iron-regulated transcriptional activator AFT1

1

0

High-throughput

0.438

High

979567

DYN3
Cytoplasmic dynein intermediate light chain DYN3

1

0

High-throughput

0.438

High

979572

NBA1
Protein NBA1

1

0

High-throughput

0.438

High

979588

FYV1
Putative uncharacterized protein FYV1

1

0

High-throughput

0.438

High

663254

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.437

High

797576

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

3

High-throughput

0.437

High

860371

EIF2A
Eukaryotic translation initiation factor 2A

1

2

High-throughput

0.437

High

863635

COPA
Coatomer subunit alpha

1

3

High-throughput

0.437

High

979148

PDS5
Sister chromatid cohesion protein PDS5

1

1

High-throughput

0.437

High

979576

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.437

High

424705

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

641059

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.426

High

817402

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.426

High

859201

ARI1
NADPH-dependent aldehyde reductase ARI1

1

0

High-throughput

0.426

High

979580

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

979582

YDR10
Uncharacterized protein YDR010C

1

1

High-throughput

0.417

High

734043

NU133
Nucleoporin NUP133

1

0

High-throughput

0.282

High

770108

RT106
Histone chaperone RTT106

1

0

High-throughput

0.282

High

864764

MNT4
Probable alpha-1,3-mannosyltransferase MNT4

1

0

High-throughput

0.282

High

747959

MCFS2
Medium-chain fatty acid ethyl ester synthase/esterase 2

1

0

High-throughput

0.279

Low

711019

YKJ7
Uncharacterized protein YKL097C

1

0

High-throughput

0.261

Low

864524

ZRG17
Protein ZRG17

1

0

High-throughput

0.261

Low

960076

RGM1
Probable transcription repressor protein RGM1

1

0

High-throughput

0.261

Low

699991

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

0

High-throughput

0.249

Low

812116

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.249

Low

978266

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

979587

ATG40
Autophagy-related protein 40

1

0

Small-scale

0.249

Low

343149

THDH
Threonine dehydratase, mitochondrial

1

0

High-throughput

0.238

Low

630532

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.238

Low

979571

YAP7
AP-1-like transcription factor YAP7

1

0

High-throughput

0.238

Low

728210

NU120
Nucleoporin NUP120

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024