HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: CRK (P46108)
Adapter molecule crk (Proto-oncogene c-Crk) (p38)
Gene: CRK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	17474147
Identification Methods	peptide array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1043 Hs			1 304
+	Hs
		551424 RAG1_HUMAN (1-1043): 0: 1703: 100.00		PLCG1_HUMAN (1-302): 7.99e-27: 112: 15.39
+	Hs
		551423 RAG1_HUMAN (1-1043): 0: 1703: 100.00		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		802727 RNF41_HUMAN (283-468): 1.49e-37: 145: 20.00		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		802736 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		CRK_HUMAN (1-304): 7.82e-68: 215: 100.00
+	Hs
		275202 TRI68_HUMAN (278-588): 4.96e-36: 145: 11.24		GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17
+	Mm
		936290 TRAF6_MOUSE (281-451): 5.96e-31: 130: 20.12		VAV3_MOUSE (11-189): 3.49e-34: 133: 25.64
+	Mm
		1143604 TRI27_MOUSE (278-550): 3.48e-38: 152: 13.24		PLCG2_MOUSE (11-301): 1.34e-25: 108: 16.40
+	Hs
		1356641 TRAF6_HUMAN (281-424): 2.9e-29: 125: 22.00		VAV3_HUMAN (11-189): 1.56e-33: 131: 26.15
+	Hs
		536781 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		275214 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		GRAP2_HUMAN (1-296): 5.17e-33: 125: 17.17
+	Hs
		924879 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		924718 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		GRB2_HUMAN (135-297): 2.78e-25: 102: 15.67
+	Hs
		208986 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Hs
		1331810 RNF41_HUMAN (283-468): 1.49e-37: 145: 20.00		ITSN2_HUMAN (189-304): 5.82e-12: 68.3: 11.86
+	Hs
		1331819 RNF41_HUMAN (283-468): 1.49e-37: 145: 20.00		CD2AP_HUMAN (1-196): 4.74e-12: 68.3: 17.12
+	Hs
		557799 TRI39_HUMAN (284-466): 6.32e-34: 139: 14.05		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00
+	Hs
		209122 LNX1_HUMAN (258-402): 6.57e-27: 120: 24.66		NCK2_HUMAN (2-100): 3.06e-11: 65.2: 18.00
+	Hs
		584954 RO52_HUMAN (79-206): 1.07e-12: 73.7: 12.40		GRAP_HUMAN (135-294): 3.79e-21: 91.4: 16.67
+	Hs
		1078906 TRIM5_HUMAN (71-272): 6.46e-16: 84.1: 10.63		ITSN1_HUMAN (150-302): 3.02e-10: 63.3: 13.87
+	Hs
		557626 BRCA1_HUMAN (291-361): 2.22e-09: 63.9: 28.77		NCK1_HUMAN (2-100): 1.55e-10: 63.3: 18.00