HitPredict

Interactor 1: RAG1 (P15918)
V(D)J recombination-activating protein 1 (RAG-1) (RING finger protein 74) [Includes: Endonuclease RAG1 (EC 3.1.-.-); E3 ubiquitin-protein ligase RAG1 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase RAG1)]
Gene: RAG1

Interactor 2: UB2R1 (P49427)
Ubiquitin-conjugating enzyme E2 R1 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme R1) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme R1) (Ubiquitin-conjugating enzyme E2-32 kDa complementing) (Ubiquitin-conjugating enzyme E2-CDC34) (Ubiquitin-protein ligase R1)
Gene: CDC34

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	19118899
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UQ_con~zf-C3HC4
Common GO terms	GO:0004842 - ubiquitin-protein transferase activity GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1043 Hs			1 236
+	Hs
		551428 RAG1_HUMAN (1-1043): 0: 1703: 100.00		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		551434 RAG1_HUMAN (1-1043): 0: 1703: 100.00		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		849377 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		919794 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		895854 COP1_HUMAN (278-587): 9.57e-53: 200: 20.48		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		1285831 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D4_HUMAN (9-167): 3e-71: 216: 32.50
+	Hs
		849399 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		919816 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		895870 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		891425 TRI43_HUMAN (279-594): 1.08e-47: 178: 14.59		UB2G2_HUMAN (5-164): 8.53e-66: 203: 46.58
+	Hs
		1163056 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D4_HUMAN (9-167): 3e-71: 216: 32.50
+	Hs
		849406 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		919822 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		849344 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		895876 TRI11_HUMAN (278-618): 9.47e-40: 156: 18.21		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		919755 TRAF7_HUMAN (181-413): 9.52e-38: 153: 15.59		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		849438 TRIM7_HUMAN (288-563): 3.13e-38: 152: 16.83		UB2D1_HUMAN (9-167): 2.94e-70: 213: 34.38
+	Hs
		919852 TRIM7_HUMAN (288-563): 3.13e-38: 152: 16.83		UB2D2_HUMAN (9-167): 3.51e-70: 213: 30.00
+	Hs
		895904 TRIM7_HUMAN (288-563): 3.13e-38: 152: 16.83		UB2D3_HUMAN (9-167): 3.52e-69: 210: 29.38
+	Hs
		536757 TRI27_HUMAN (278-550): 6.23e-38: 151: 13.59		UBE2A_HUMAN (9-157): 1.04e-26: 102: 38.26