HitPredict - High confidence protein-protein interactions

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	24126761, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RPA_C~RPA_C
Common GO terms	GO:0000723 - telomere maintenance GO:0000724 - double-strand break repair via homologous recombination GO:0000781 - chromosome, telomeric region GO:0000785 - chromatin GO:0003684 - damaged DNA binding and 20 others more... GO:0003697 - single-stranded DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005662 - DNA replication factor A complex GO:0006260 - DNA replication GO:0006284 - base-excision repair GO:0006289 - nucleotide-excision repair GO:0006298 - mismatch repair GO:0010569 - regulation of double-strand break repair via homologous recombination GO:0016604 - nuclear body GO:0016605 - PML body GO:0019899 - enzyme binding GO:0019903 - protein phosphatase binding GO:0031571 - mitotic G1 DNA damage checkpoint signaling GO:0031625 - ubiquitin protein ligase binding GO:0034502 - protein localization to chromosome GO:0035861 - site of double-strand break GO:0042162 - telomeric DNA binding GO:0098505 - G-rich strand telomeric DNA binding GO:2000001 - regulation of DNA damage checkpoint
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	270
Hs

1	270

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Last updated: 15 Jul 2024