HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 21664290
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 2843
+	Hs
		626120 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		APC_HUMAN (1-2843): 0: 1316: 100.00
+	Hs
		554174 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41
+	Hs
		554074 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SRRM2_HUMAN (943-2827): 1.37e-30: 135: 8.96
+	Hs
		552003 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		552728 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		MDC1_HUMAN (1750-2784): 3.28e-21: 104: 11.74
+	Hs
		552197 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24
+	Hs
		553487 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		CIC_HUMAN (722-2643): 2.1e-17: 92.4: 7.79
+	Hs
		553224 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		KMT2C_HUMAN (2340-2838): 4.14e-09: 64.9: 8.02
+	Hs
		653969 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		MAP4_HUMAN (2119-2724): 1.19e-29: 131: 15.90
+	Hs
		820906 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		PRC2A_HUMAN (951-2843): 2.17e-19: 98.6: 7.24