Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: RFA3 (P35244)
Replication protein A 14 kDa subunit (RP-A p14) (Replication factor A protein 3) (RF-A protein 3)
Gene: RPA3

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 24126761, 9461578, 17976647, 37827155, 26186194, 28514442, 8663296, 24981860, 33961781, 11927569, 8663111, 8290566, 34591612, 22977173, 19338310, 8157639, 8972858, 7760808, 10336450, 12509449 and 4 others

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Identification Methods affinity chromatography technology, biochemical, x-ray crystallography, proximity labelling technology, two hybrid, molecular sieving, coimmunoprecipitation, cosedimentation in solution, cosedimentation through density gradient, tandem affinity purification and 2 others

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Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000723 - telomere maintenance
GO:0000724 - double-strand break repair via homologous recombination
GO:0003684 - damaged DNA binding
GO:0003697 - single-stranded DNA binding
GO:0005654 - nucleoplasm
and 6 others

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Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 270
Hs

1 121
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024