HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1)
Gene: MTOR

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	37827155
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 2549
+	Hs
		787469 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		MTOR_HUMAN (1-2549): 0: 2102: 100.00
+	Hs
		552637 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		ATM_HUMAN (387-2548): 0: 894: 14.98
+	Hs
		552661 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		ATR_HUMAN (186-2548): 0: 816: 14.82
+	Hs
		554140 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		TRRAP_HUMAN (925-2548): 0: 720: 15.53
+	Hs
		552483 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		PRKDC_HUMAN (695-2548): 0: 686: 14.83
+	Hs
		1026601 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		TRRAP_HUMAN (925-2548): 0: 720: 15.53
+	Hs
		553480 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		SMG1_HUMAN (1557-2531): 1.86e-123: 441: 18.35
+	Sc
		644751 RFA2_YEAST (4-264): 9.48e-71: 220: 25.61		ATM_YEAST (1223-2549): 6.86e-154: 538: 15.87
+	Hs
		553325 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		GCN1_HUMAN (245-1372): 1.05e-38: 162: 12.17
+	Sc
		644752 RFA2_YEAST (4-264): 9.48e-71: 220: 25.61		ATR_YEAST (2477-2549): 3.41e-11: 71.7: 31.51