HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: TIF1B (Q13263)
Transcription intermediary factor 1-beta (TIF1-beta) (E3 SUMO-protein ligase TRIM28) (EC 2.3.2.27) (KRAB-associated protein 1) (KAP-1) (KRAB-interacting protein 1) (KRIP-1) (Nuclear corepressor KAP-1) (RING finger protein 96) (RING-type E3 ubiquitin transferase TIF1-beta) (Tripartite motif-containing protein 28)
Gene: TRIM28

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	37827155, 24332808
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 835
+	Hs
		1026395 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		TIF1B_HUMAN (18-835): 3.77e-174: 525: 100.00
+	Hs
		175637 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		TRI18_HUMAN (56-644): 5.73e-67: 237: 13.78
+	Hs
		554064 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		TRI33_HUMAN (406-826): 1.6e-54: 206: 19.32
+	Hs
		170244 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		TIF1A_HUMAN (404-808): 1.31e-52: 200: 21.55