Interactor 1: LOX5 (P12527)
Polyunsaturated fatty acid 5-lipoxygenase (EC 1.13.11.-) (Arachidonate 5-lipoxygenase) (5-LO) (5-lipoxygenase) (EC 1.13.11.34)
Gene: Alox5
Interactor 2: AL5AP (P20291)
Arachidonate 5-lipoxygenase-activating protein (FLAP) (MK-886-binding protein)
Gene: Alox5ap
Species: Rattus norvegicus
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.40 | 0.60 | 0.494 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 19075240 |
| Identification Methods | fluorescence microscopy, anti bait coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0002540 - leukotriene production involved in inflammatory response GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0019370 - leukotriene biosynthetic process GO:0019372 - lipoxygenase pathway and 1 others more... |
| Homologous interactions | 3 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
