HitPredict

Interactor 1: RFA2 (P15927)
Replication protein A 32 kDa subunit (RP-A p32) (Replication factor A protein 2) (RF-A protein 2) (Replication protein A 34 kDa subunit) (RP-A p34)
Gene: RPA2

Interactor 2: SP16H (Q9Y5B9)
FACT complex subunit SPT16 (Chromatin-specific transcription elongation factor 140 kDa subunit) (FACT 140 kDa subunit) (FACTp140) (Facilitates chromatin transcription complex subunit SPT16) (hSPT16)
Gene: SUPT16H

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	26186194, 28514442, 33961781, 37827155
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006260 - DNA replication
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 1047
+	Hs
		1026606 RFA4_HUMAN (1-268): 6.87e-96: 283: 45.56		SP16H_HUMAN (1-1047): 0: 1331: 100.00
+	Sc
		644741 RFA2_YEAST (4-264): 9.48e-71: 220: 25.61		SPT16_YEAST (3-1008): 0: 938: 33.49
+	Hs
		553808 RFA2_HUMAN (1-270): 1.68e-127: 364: 100.00		XPP1_HUMAN (63-437): 1e-70: 249: 14.94