HitPredict

Interactor 1: MUC1 (P15941)
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
Gene: MUC1

Interactor 2: HSP74 (P34932)
Heat shock 70 kDa protein 4 (HSP70RY) (Heat shock 70-related protein APG-2) (Heat shock protein family H member 2)
Gene: HSPA4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	16158055
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0070062 - extracellular exosome
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 840
+	Hs
		714143 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		HSP74_HUMAN (1-840): 0: 993: 100.00
+	Dm
		1370298 Q9VLS7_DROME (4-946): 1.2e-18: 94.7: 11.85		Q9VUC1_DROME (1-840): 0: 821: 42.10
+	Hs
		503713 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504619 MINT_HUMAN (22-1062): 3.99e-14: 80.1: 9.50		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		131685 BCL9_HUMAN (150-1126): 4.42e-13: 76.3: 8.09		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		146144 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504971 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92
+	Hs
		504789 MUC5B_HUMAN (203-1090): 2.97e-09: 64: 10.14		HSP7C_HUMAN (564-692): 5.97e-20: 97: 16.92