Protein: GDF11
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)

Gene: GDF11
Organism: Homo sapiens
Interactions: 45
UniProt ID: O95390

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0001656 - metanephros development
GO:0001657 - ureteric bud development
GO:0005125 - cytokine activity
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

335387

AVR2B
Activin receptor type-2B

2

20

Small-scale

0.799

High

164752

GDF8
Growth/differentiation factor 8

1

17

High-throughput

0.691

High

335378

BMP7
Bone morphogenetic protein 7

1

16

High-throughput

0.691

High

335390

PRTG
Protogenin

1

2

High-throughput

0.691

High

335397

LIPH
Lipase member H

3

2

High-throughput

0.667

High

335371

CRP

3

3

High-throughput

0.662

High

335372

A4
Amyloid-beta precursor protein

2

18

High-throughput

0.628

High

335384

SG2A2
Mammaglobin-A

2

3

High-throughput

0.628

High

335406

DKK3
Dickkopf-related protein 3

2

1

High-throughput

0.628

High

335408

PCDG5
Protocadherin gamma-A5

2

1

High-throughput

0.628

High

335394

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

2

High-throughput

0.618

High

335392

TMM25
Transmembrane protein 25

3

1

High-throughput

0.609

High

335404

SIAE
Sialate O-acetylesterase

2

0

High-throughput

0.585

High

335396

CA054
Uncharacterized protein C1orf54

2

5

High-throughput

0.549

High

316645

LY6H
Lymphocyte antigen 6H

1

3

High-throughput

0.536

High

335373

TRY2
Trypsin-2

1

8

High-throughput

0.536

High

335374

CCL3
C-C motif chemokine 3

1

3

High-throughput

0.536

High

335375

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.536

High

335376

TDGF1
Protein Cripto

1

8

High-throughput

0.536

High

335377

EDN3
Endothelin-3

1

1

High-throughput

0.536

High

335381

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

2

High-throughput

0.536

High

335388

PRSS8
Prostasin

1

6

High-throughput

0.536

High

335389

CL12B
C-type lectin domain family 12 member B

1

2

High-throughput

0.536

High

335401

C1QT7
Complement C1q tumor necrosis factor-related protein 7

1

12

High-throughput

0.536

High

335405

MMP26
Matrix metalloproteinase-26

1

4

High-throughput

0.536

High

335407

FBLN5
Fibulin-5

1

12

High-throughput

0.536

High

73755

C1T9B
Complement C1q and tumor necrosis factor-related protein 9B

1

13

High-throughput

0.489

High

335382

EP3B
Epididymal secretory protein E3-beta

1

1

High-throughput

0.489

High

335383

LCN6
Epididymal-specific lipocalin-6

1

2

High-throughput

0.489

High

335386

OS9
Protein OS-9

1

3

High-throughput

0.489

High

335399

LCFC1
Sperm-egg fusion protein LLCFC1

1

1

High-throughput

0.489

High

335402

CAD23
Cadherin-23

1

5

High-throughput

0.489

High

335395

WFKN2
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2

1

19

Small-scale

0.479

High

335400

WFKN1
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 1

1

13

Small-scale

0.479

High

335398

ERLEC
Endoplasmic reticulum lectin 1

1

3

High-throughput

0.437

High

335403

ANTR1
Anthrax toxin receptor 1

1

1

High-throughput

0.437

High

335391

LYPD4
Ly6/PLAUR domain-containing protein 4

2

0

High-throughput

0.328

High

66540

TSPY2
Testis-specific Y-encoded protein 2

1

0

High-throughput

0.279

Low

231292

EFNA2
Ephrin-A2

1

0

High-throughput

0.279

Low

249352

PLXC1
Plexin-C1

1

0

High-throughput

0.279

Low

335379

MAT1
CDK-activating kinase assembly factor MAT1

1

0

High-throughput

0.279

Low

335380

ZN131
Zinc finger protein 131

1

0

High-throughput

0.279

Low

335385

MFAP5
Microfibrillar-associated protein 5

1

0

High-throughput

0.279

Low

335393

DB125
Beta-defensin 125

1

0

High-throughput

0.279

Low

222610

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025