HitPredict

Interactor 1: MUC1 (P15941)
Mucin-1 (MUC-1) (Breast carcinoma-associated antigen DF3) (Cancer antigen 15-3) (CA 15-3) (Carcinoma-associated mucin) (Episialin) (H23AG) (Krebs von den Lungen-6) (KL-6) (PEMT) (Peanut-reactive urinary mucin) (PUM) (Polymorphic epithelial mucin) (PEM) (Tumor-associated epithelial membrane antigen) (EMA) (Tumor-associated mucin) (CD antigen CD227) [Cleaved into: Mucin-1 subunit alpha (MUC1-NT) (MUC1-alpha); Mucin-1 subunit beta (MUC1-beta) (MUC1-CT)]
Gene: MUC1

Interactor 2: WWP1 (Q9H0M0)
NEDD4-like E3 ubiquitin-protein ligase WWP1 (EC 2.3.2.26) (Atrophin-1-interacting protein 5) (AIP5) (HECT-type E3 ubiquitin transferase WWP1) (TGIF-interacting ubiquitin ligase 1) (Tiul1) (WW domain-containing protein 1)
Gene: WWP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35264565
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1255 Hs			1 922
+	Hs
		869535 ATN1_HUMAN (1-875): 7.71e-09: 62.5: 12.06		WWP1_HUMAN (1-922): 0: 953: 100.00
+	Hs
		125261 HCFC1_HUMAN (7-1107): 6.45e-29: 128: 11.01		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		1294841 MINT_HUMAN (22-1062): 3.99e-14: 80.1: 9.50		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		146268 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		869511 ATN1_HUMAN (1-875): 7.71e-09: 62.5: 12.06		ITCH_HUMAN (1-922): 0: 884: 57.14
+	Hs
		124994 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125556 Q86V38_HUMAN (457-1150): 1.22e-09: 65.2: 10.09		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125795 SRRM2_HUMAN (105-1020): 1.64e-09: 64.9: 7.41		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		125277 ATN1_HUMAN (1-875): 7.71e-09: 62.5: 12.06		WWP2_HUMAN (1-922): 0: 841: 57.84
+	Hs
		146175 ARI1A_HUMAN (9-962): 3.38e-11: 70.2: 10.06		NEDD4_HUMAN (84-919): 0: 723: 33.52
+	Dm
		1370333 Q9VLS7_DROME (4-946): 1.2e-18: 94.7: 11.85		Q9VXR3_DROME (304-920): 9.33e-163: 530: 29.11
+	Hs
		1170093 SRCAP_HUMAN (1-542): 4.23e-12: 73.5: 13.50		HECW2_HUMAN (141-582): 1.9e-12: 73.8: 16.11