HitPredict

Interactor 1: MET (P16056)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Interactor 2: TEN2 (Q9WTS5)
Teneurin-2 (Ten-2) (Protein Odd Oz/ten-m homolog 2) (Tenascin-M2) (Ten-m2) (Teneurin transmembrane protein 2) [Cleaved into: Ten-2, soluble form; Ten-2 intracellular domain (Ten-2 ICD)]
Gene: Tenm2

Species: Mus musculus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27086544
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0030425 - dendrite GO:0045211 - postsynaptic membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1379 Mm			1 2764
+	Mm
		554990 MET_MOUSE (1-1379): 0: 1369: 100.00		TEN4_MOUSE (1-2764): 0: 2950: 61.65
+	Mm
		101584 F8VQL0_MOUSE (1-1379): 0: 1368: 99.86		TEN4_MOUSE (1-2764): 0: 2950: 61.65
+	Mm
		101609 F8VQL0_MOUSE (1-1379): 0: 1368: 99.86		TEN1_MOUSE (6-2764): 0: 2899: 55.43
+	Mm
		57475 MET_MOUSE (1-1379): 0: 1369: 100.00		A2ANL9_MOUSE (6-2764): 0: 2882: 55.32
+	Hs
		1072545 EPHA7_HUMAN (576-1373): 8.31e-158: 503: 18.73		VWDE_HUMAN (555-796): 5.05e-59: 228: 31.10
+	Hs
		872428 EPHA5_HUMAN (576-1364): 1.29e-171: 541: 18.81		NOTC2_HUMAN (765-1097): 5.26e-25: 117: 14.37
+	Hs
		872634 EPHA4_HUMAN (576-1368): 9.35e-169: 532: 17.67		NOTC2_HUMAN (765-1097): 5.26e-25: 117: 14.37
+	Hs
		980379 EPHA7_HUMAN (576-1373): 8.31e-158: 503: 18.73		NOTC2_HUMAN (765-1097): 5.26e-25: 117: 14.37
+	Hs
		665584 EPHB2_HUMAN (1019-1340): 7.46e-103: 354: 32.82		NOTC2_HUMAN (765-1097): 5.26e-25: 117: 14.37