HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: RD23B (P54727)
UV excision repair protein RAD23 homolog B (HR23B) (hHR23B) (XP-C repair-complementing complex 58 kDa protein) (p58)
Gene: RAD23B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28242625
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Histone~ubiquitin
Common GO terms	GO:0003684 - damaged DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0007283 - spermatogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 143 Hs			1 409
+	Hs
		391613 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		RD23B_HUMAN (1-409): 1.31e-125: 370: 100.00
+	Hs
		1312243 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		UBQL1_HUMAN (1-404): 1.25e-57: 200: 13.72
+	Hs
		391924 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		UBQL4_HUMAN (1-364): 2.75e-45: 166: 12.71
+	Hs
		474911 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		UBB_HUMAN (1-79): 1.99e-32: 123: 30.38
+	Hs
		555404 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		924397 H2A1J_HUMAN (1-128): 1.45e-66: 199: 92.19		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		924374 H2A1C_HUMAN (1-129): 5.04e-66: 198: 92.25		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		924387 H2A1H_HUMAN (1-128): 2.85e-66: 198: 92.19		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		391644 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		470332 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		924322 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	Hs
		924334 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		RL40_HUMAN (1-91): 3.57e-33: 122: 28.57
+	At
		1092092 H2A6_ARATH (1-128): 3.9e-61: 186: 73.64		UBQ3_ARATH (1-80): 7.66e-29: 116: 28.75
+	Hs
		555403 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Dm
		950447 H2A_DROME (17-124): 3.82e-60: 183: 90.74		R9PY16_DROME (1-71): 4.45e-25: 105: 33.80
+	Hs
		391643 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		470331 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		924034 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		924049 H2A3_HUMAN (1-129): 5.88e-66: 197: 91.47		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67
+	Hs
		260831 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		RS27A_HUMAN (1-90): 2.4e-15: 75: 26.67