HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: NP1L1 (P55209)
Nucleosome assembly protein 1-like 1 (NAP-1-related protein) (hNRP)
Gene: NAP1L1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	1.00	0.903

Property	Details
Experiments	24981860, 28514442, 28242625, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~NAP
Common GO terms	GO:0005634 - nucleus GO:0006334 - nucleosome assembly GO:0042393 - histone binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 391
+	Hs
		876839 H2A2B_HUMAN (1-128): 3.43e-66: 198: 92.97		NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00
+	Hs
		391616 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00
+	Hs
		470307 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00
+	Hs
		876804 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00
+	Hs
		260812 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		NP1L1_HUMAN (1-391): 7.29e-142: 410: 100.00
+	Hs
		391863 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03
+	Hs
		470518 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03
+	Hs
		1087091 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		NP1L4_HUMAN (12-353): 2.19e-130: 380: 65.03
+	Dm
		950430 H2A_DROME (17-124): 3.82e-60: 183: 90.74		Q24150_DROME (10-391): 3.64e-120: 354: 44.16
+	Dm
		950446 H2A_DROME (17-124): 3.82e-60: 183: 90.74		Q9W1G7_DROME (10-391): 4.29e-120: 354: 44.16
+	Sc
		392059 H2A1_YEAST (16-142): 1.37e-53: 166: 75.59		NAP1_YEAST (16-390): 4.36e-102: 310: 30.61
+	Sc
		392309 H2A2_YEAST (16-124): 4.61e-53: 165: 82.57		NAP1_YEAST (16-390): 4.36e-102: 310: 30.61
+	Ce
		452190 H2A_CAEEL (17-121): 9.95e-55: 169: 91.43		Q19007_CAEEL (51-371): 1.19e-88: 272: 40.62
+	Hs
		391771 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		TSYL5_HUMAN (18-357): 2.73e-64: 212: 15.91
+	Hs
		555417 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		SET_HUMAN (62-343): 2.66e-57: 190: 20.28
+	Hs
		260925 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		TSYL5_HUMAN (18-357): 2.73e-64: 212: 15.91
+	Hs
		391896 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		TSYL1_HUMAN (71-343): 7.16e-63: 209: 18.32
+	Hs
		260844 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		SET_HUMAN (62-343): 2.66e-57: 190: 20.28