HitPredict

Interactor 1: H2AX (P16104)
Histone H2AX (H2a/x) (Histone H2A.X)
Gene: H2AX

Interactor 2: MIER1 (Q8N108)
Mesoderm induction early response protein 1 (Early response 1) (Er1) (Mi-er1) (hMi-er1)
Gene: MIER1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.675

Property	Details
Experiments	24981860, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 143 Hs			1 512
+	Hs
		1151354 H2A2A_HUMAN (1-129): 7e-66: 197: 91.47		MIER1_HUMAN (1-512): 2.64e-159: 464: 100.00
+	Hs
		391790 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		MIER1_HUMAN (1-512): 2.64e-159: 464: 100.00
+	Hs
		470456 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		MIER1_HUMAN (1-512): 2.64e-159: 464: 100.00
+	Hs
		1087048 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		MIER1_HUMAN (1-512): 2.64e-159: 464: 100.00
+	Hs
		1229950 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		MIER1_HUMAN (1-512): 2.64e-159: 464: 100.00
+	Hs
		555525 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MIER3_HUMAN (1-488): 8.98e-132: 395: 46.83
+	Hs
		391763 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		MIER3_HUMAN (1-488): 8.98e-132: 395: 46.83
+	Hs
		470435 H2A1_HUMAN (1-129): 7.56e-66: 197: 91.47		MIER3_HUMAN (1-488): 8.98e-132: 395: 46.83
+	Hs
		1087032 H2A2C_HUMAN (1-129): 5.09e-65: 195: 90.70		MIER3_HUMAN (1-488): 8.98e-132: 395: 46.83
+	Hs
		1189332 H2AJ_HUMAN (1-125): 5.62e-65: 195: 93.60		MIER3_HUMAN (1-488): 8.98e-132: 395: 46.83
+	Hs
		555628 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MTA3_HUMAN (94-483): 1.03e-106: 332: 16.14
+	Hs
		295927 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MTA2_HUMAN (94-501): 7.93e-98: 311: 17.62
+	Hs
		555449 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		MTA1_HUMAN (94-507): 2.51e-93: 300: 16.00
+	Hs
		260687 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		MTA2_HUMAN (94-501): 7.93e-98: 311: 17.62
+	Hs
		260873 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		MTA1_HUMAN (94-507): 2.51e-93: 300: 16.00
+	Hs
		555685 H2AX_HUMAN (1-143): 3.71e-74: 219: 100.00		RCOR1_HUMAN (180-512): 8.2e-67: 225: 17.26
+	Hs
		391753 H2A1B_HUMAN (1-129): 8.35e-66: 197: 90.70		MDEAS_HUMAN (94-457): 1.74e-64: 228: 15.67
+	Hs
		261035 H2AY_HUMAN (1-142): 1.74e-61: 194: 60.69		RCOR1_HUMAN (180-512): 8.2e-67: 225: 17.26