HitPredict

Interactor 1: VATB (P16140)
V-type proton ATPase subunit B (V-ATPase subunit B) (V-ATPase 57 kDa subunit) (Vacuolar proton pump subunit B)
Gene: VMA2

Interactor 2: VATA (P17255)
V-type proton ATPase catalytic subunit A (V-ATPase subunit A) (EC 7.1.2.2) (Vacuolar proton pump subunit A) [Cleaved into: Endonuclease PI-SceI (EC 3.1.-.-) (Sce VMA intein) (VMA1-derived endonuclease) (VDE)]
Gene: VMA1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 11844802, 8626613, 11805826, 23142977, 11717306, 30910982, 22940862, 16554755, 16429126, 16926153, 18344484, 37968396
Identification Methods coimmunoprecipitation, two hybrid, tandem affinity purification, anti tag coimmunoprecipitation, affinity chromatography technology, biochemical, x-ray crystallography
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATP-synt_ab~ATP-synt_ab, ATP-synt_ab~ATP-synt_ab_N, ATP-synt_ab~ATP-synt_ab_Xtn, ATP-synt_ab_N~ATP-synt_ab_N, ATP-synt_ab_N~ATP-synt_ab_Xtn
Common GO terms GO:0000139 - Golgi membrane
GO:0000221 - vacuolar proton-transporting V-type ATPase, V1 domain
GO:0000329 - fungal-type vacuole membrane
GO:0005524 - ATP binding
GO:0007035 - vacuolar acidification
and 6 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 517
Sc

1 1071
+ Hs
+ Dm
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Sc
+ Hs
+ Hs
+ Dm
+ Nv
+ Tt
+ Sc
+ Ce
+ Sc

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Last updated: 15 Jul 2024