Interactor 1: CREB1 (P16220)
Cyclic AMP-responsive element-binding protein 1 (CREB-1) (cAMP-responsive element-binding protein 1)
Gene: CREB1

Interactor 2: CBP (Q92793)
CREB-binding protein (Histone lysine acetyltransferase CREBBP) (EC 2.3.1.48) (Protein lactyltransferas CREBBP) (EC 2.3.1.-) (Protein-lysine acetyltransferase CREBBP) (EC 2.3.1.-)
Gene: CREBBP

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 8413673, 12933667, 27789289, 9786917, 12196545, 36477795, 7870179, 8028671, 15073328, 17707401, 15691881, 23671189, 8663317, 9413984, 10848610, 10866654, 11259575, 12198160, 17209043, 18599546 and 9 others

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Identification Methods pull down, far western blotting, affinity chromatography technology, fluorescent resonance energy transfer, two hybrid, x-ray crystallography, experimental interaction detection, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains KIX~pKID
Common GO terms GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0007165 - signal transduction
GO:0045893 - positive regulation of DNA-templated transcription
and 2 others

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Homologous interactions 6

Homologous interactions

Color coding for hit scores

1 327
Hs

1 2442
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024