HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: CDN2B (P42772)
Cyclin-dependent kinase 4 inhibitor B (Multiple tumor suppressor 2) (MTS-2) (p14-INK4b) (p15-INK4b) (p15INK4B)
Gene: CDKN2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	28205554
Identification Methods	fluorescent resonance energy transfer
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	Ank_2~I-set
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Hs			1 138
+	Hs
		557060 PGFRA_HUMAN (1-1089): 0: 817: 100.00		CDN2A_HUMAN (9-137): 9.34e-55: 170: 81.96
+	Hs
		557062 PGFRA_HUMAN (1-1089): 0: 817: 100.00		CDN2C_HUMAN (18-137): 2.41e-39: 131: 44.17
+	Hs
		557108 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ANK3_HUMAN (51-138): 9.18e-23: 94.7: 20.46
+	Hs
		557289 PGFRA_HUMAN (1-1089): 0: 817: 100.00		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93
+	Hs
		609438 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		FANK1_HUMAN (18-137): 7.42e-32: 117: 23.77
+	Hs
		1083910 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		ANR26_HUMAN (18-138): 4.03e-33: 124: 23.58
+	Hs
		607908 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2A_HUMAN (9-137): 9.34e-55: 170: 81.96
+	Hs
		1083907 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93
+	Hs
		601612 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93
+	Hs
		607909 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2B_HUMAN (1-138): 2.59e-45: 145: 100.00
+	Hs
		607910 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		CDN2C_HUMAN (18-137): 2.41e-39: 131: 44.17
+	Hs
		608197 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		ANR26_HUMAN (18-138): 4.03e-33: 124: 23.58
+	Hs
		507831 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK1_HUMAN (10-138): 7.16e-33: 123: 20.77
+	Hs
		434183 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		ANK3_HUMAN (51-138): 9.18e-23: 94.7: 20.46
+	Hs
		507971 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK3_HUMAN (51-138): 9.18e-23: 94.7: 20.46
+	Hs
		608184 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93
+	Hs
		608115 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		TANC1_HUMAN (58-136): 1.31e-11: 62.7: 23.75
+	Hs
		507954 FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71		ANK2_HUMAN (1-65): 9.67e-17: 77.3: 22.73
+	Hs
		674564 UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93
+	Hs
		427015 CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59		KDIS_HUMAN (1-83): 3.39e-14: 70: 20.93