HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: SNTB2 (Q13425)
Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL)
Gene: SNTB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~PK_Tyr_Ser-Thr
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005794 - Golgi apparatus GO:0005886 - plasma membrane GO:0016020 - membrane and 1 others more... GO:0032991 - protein-containing complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1089 Hs			1 540
+	Hs
		452413 PGFRB_HUMAN (29-1089): 0: 650: 43.33		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		452421 PGFRB_HUMAN (29-1089): 0: 650: 43.33		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Ce
		1014310 EGL15_CAEEL (5-1072): 3.56e-155: 490: 16.61		SNT1_CAEEL (84-538): 8.28e-114: 346: 37.64
+	Hs
		452485 PGFRB_HUMAN (29-1089): 0: 650: 43.33		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		609274 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		609282 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		280015 KIT_HUMAN (18-978): 0: 559: 33.64		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		607960 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		SNTB2_HUMAN (18-540): 1.13e-164: 480: 100.00
+	Hs
		607963 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		729276 VGFR3_HUMAN (128-609): 7.49e-19: 94.9: 11.28		SNTB1_HUMAN (24-539): 2.43e-151: 445: 55.30
+	Hs
		609552 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		280018 FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74		MPDZ_HUMAN (13-297): 7.06e-17: 86.5: 16.07
+	Hs
		1083899 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		601598 FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Mm
		546303 NTRK2_MOUSE (53-776): 3.36e-53: 202: 13.62		DLG4_MOUSE (66-394): 4.96e-27: 117: 16.32
+	Hs
		942352 NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04		DLG4_HUMAN (66-394): 4.83e-27: 117: 16.02
+	Hs
		434291 RET_HUMAN (573-690): 7.85e-22: 104: 43.22		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		608144 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		427011 CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59		GOPC_HUMAN (92-199): 1.67e-34: 137: 39.82
+	Hs
		674412 UFO_HUMAN (13-225): 2.38e-15: 83.4: 14.71		DLG1_HUMAN (2-419): 1.78e-27: 119: 15.51