Protein: TEC
Tyrosine-protein kinase Tec (EC 2.7.10.2)

Gene: TEC
Organism: Homo sapiens
Interactions: 69
UniProt ID: P42680

Gene Ontology (top 5):
GO:0002250 - adaptive immune response
GO:0004715 - non-membrane spanning protein tyrosine kinase activity
GO:0005524 - ATP binding
GO:0005543 - phospholipid binding
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

532056

KIT
Mast/stem cell growth factor receptor Kit

3

20

Small-scale

0.870

High

840894

DOK1
Docking protein 1

2

20

Small-scale

0.825

High

193227

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.783

High

253321

JAK2
Tyrosine-protein kinase JAK2

2

20

Small-scale

0.768

High

840887

ANR54
Ankyrin repeat domain-containing protein 54

2

15

High-throughput

0.705

High

472017

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.692

High

840880

GAB1
GRB2-associated-binding protein 1

1

20

High-throughput

0.692

High

840863

FRK
Tyrosine-protein kinase FRK

1

19

High-throughput

0.691

High

840869

SEC13
Protein SEC13 homolog

1

2

High-throughput

0.691

High

840871

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.691

High

840884

CNN3
Calponin-3

1

5

High-throughput

0.691

High

362924

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.647

High

410689

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

641511

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

High-throughput

0.647

High

840883

ERBB4
Receptor tyrosine-protein kinase erbB-4

1

20

High-throughput

0.647

High

840886

LRRK1
Leucine-rich repeat serine/threonine-protein kinase 1

1

20

High-throughput

0.647

High

840898

ARHGC
Rho guanine nucleotide exchange factor 12

1

18

Small-scale

0.647

High

840901

ASAP1
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1

1

15

Small-scale

0.647

High

136323

P85B
Phosphatidylinositol 3-kinase regulatory subunit beta

1

20

Small-scale

0.621

High

463388

LYN
Tyrosine-protein kinase Lyn

1

19

Small-scale

0.618

High

584487

VAV
Proto-oncogene vav

1

20

Small-scale

0.618

High

658652

JAK1
Tyrosine-protein kinase JAK1

1

20

Small-scale

0.618

High

711270

SHC1
SHC-transforming protein 1

1

20

High-throughput

0.618

High

840906

SNX9
Sorting nexin-9

1

7

High-throughput

0.618

High

471733

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.575

High

658812

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

High-throughput

0.575

High

658998

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

20

High-throughput

0.575

High

840875

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

20

High-throughput

0.575

High

840877

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.575

High

840882

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.575

High

840885

PTPRO
Receptor-type tyrosine-protein phosphatase O

1

20

High-throughput

0.575

High

596942

PRLR
Prolactin receptor

1

20

Small-scale

0.561

High

840907

NEMO
NF-kappa-B essential modulator

1

20

High-throughput

0.561

High

840903

TUTLB
Protein turtle homolog B

1

9

High-throughput

0.553

High

840872

ADAM8
Disintegrin and metalloproteinase domain-containing protein 8

1

20

Small-scale

0.536

High

840895

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

6

Small-scale

0.536

High

174960

SC16A
Protein transport protein Sec16A

1

7

High-throughput

0.536

High

775496

NU214
Nuclear pore complex protein Nup214

1

13

High-throughput

0.536

High

840866

MAP1B
Microtubule-associated protein 1B

1

10

High-throughput

0.536

High

840892

LTV1
Protein LTV1 homolog

1

1

High-throughput

0.536

High

840899

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

7

High-throughput

0.536

High

840865

WASP
Actin nucleation-promoting factor WAS

1

20

Small-scale

0.527

High

840870

UBC12
NEDD8-conjugating enzyme Ubc12

1

0

High-throughput

0.513

High

840893

SORT
Sortilin

1

0

High-throughput

0.513

High

840867

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

12

Small-scale

0.501

High

840878

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

20

Small-scale

0.501

High

840879

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

20

Small-scale

0.501

High

840896

ADA19
Disintegrin and metalloproteinase domain-containing protein 19

1

20

Small-scale

0.501

High

840904

FBX7
F-box only protein 7

1

2

High-throughput

0.501

High

840864

RBM34
RNA-binding protein 34

1

12

High-throughput

0.489

High

840876

TP53B
TP53-binding protein 1

1

3

High-throughput

0.489

High

840881

UBP2L
Ubiquitin-associated protein 2-like

1

10

High-throughput

0.489

High

840889

MISSL
MAPK-interacting and spindle-stabilizing protein-like

1

8

High-throughput

0.489

High

254076

CTND1
Catenin delta-1

1

18

High-throughput

0.479

High

339951

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

3

High-throughput

0.479

High

702419

PEX2
Peroxisome biogenesis factor 2

1

3

High-throughput

0.479

High

770444

SPRE
Sepiapterin reductase

1

6

High-throughput

0.479

High

801207

HSPA9
Stress-70 protein, mitochondrial

1

20

High-throughput

0.479

High

840868

PAXI
Paxillin

1

20

High-throughput

0.479

High

840873

GNA12
Guanine nucleotide-binding protein subunit alpha-12

1

1

Small-scale

0.479

High

840874

KMT2A
Histone-lysine N-methyltransferase 2A

1

11

High-throughput

0.479

High

840888

CYFP1
Cytoplasmic FMR1-interacting protein 1

1

8

High-throughput

0.479

High

840890

MSI2H
RNA-binding protein Musashi homolog 2

1

12

High-throughput

0.479

High

840891

CYFP2
Cytoplasmic FMR1-interacting protein 2

1

8

High-throughput

0.479

High

840900

LTOR3
Ragulator complex protein LAMTOR3

1

3

High-throughput

0.479

High

840902

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

840905

AFG32
Mitochondrial inner membrane m-AAA protease component AFG3L2

1

6

High-throughput

0.479

High

840897

MED28
Mediator of RNA polymerase II transcription subunit 28

1

8

Small-scale

0.470

High

455716

H10
Histone H1.0

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025