HitPredict

Interactor 1: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Interactor 2: SULF2 (Q8IWU5)
Extracellular sulfatase Sulf-2 (hSulf-2) (Arylsulfatase) (EC 3.1.6.1) (N-acetylglucosamine-6-sulfatase) (EC 3.1.6.14) [Cleaved into: Extracellular sulfatase Sulf-2 secreted form]
Gene: SULF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 1089 Hs			1 870
+	Hs
		557189 PGFRA_HUMAN (1-1089): 0: 817: 100.00		SULF1_HUMAN (5-870): 0: 1202: 64.75
+	Hs
		557161 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ARSK_HUMAN (36-411): 8.12e-101: 325: 23.68
+	Hs
		550453 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ARSB_HUMAN (36-439): 5.33e-98: 318: 18.06
+	Hs
		557222 PGFRA_HUMAN (1-1089): 0: 817: 100.00		ARSG_HUMAN (18-423): 1.36e-95: 311: 20.14
+	Hs
		557048 PGFRA_HUMAN (1-1089): 0: 817: 100.00		GALNS_HUMAN (42-398): 7.14e-95: 309: 22.48
+	Hs
		606857 FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36		IDS_HUMAN (45-380): 7.56e-82: 275: 19.64